Volume 9.01 | Jan 14

Cell Therapy News 9.01, January 14, 2008
     In this issue: Science | Policy | Business | NIH | CBER | Regulatory
Cell Therapy News on Facebook  Cell Therapy News on Twitter

Top Stories

Advanced Cell Technology Announces Creation of Human Embryonic Stem Cell Lines Without the Destruction of Embryos: Advanced Cell Technology, Inc. together with colleagues announced today the development of five human embryonic stem cell (hESC) lines without the destruction of embryos.


Personalized Medicine through Genomic Analysis and Molecular Diagnostics
March 31, 2008
Boston, Massachusetts

Enter “CONNEXON” at checkout and receive 10% off registration.
Click here to register today.

Fluorescent Chinese Pig Passes on Trait to Offspring
A pig genetically modified in China to make it glow has given birth to fluorescent piglets, proving such changes can be inherited.

Stem Cell Technique Wins U.S. Funding, Fuels Debate
The National Institutes of Health began accepting grant applications Jan. 5 from scientists studying an advance reported in November.

New Insight Into Factors That Drive Muscle-building Stem Cells
There is a new explanation for how stem cells known as satellite cells contribute to building muscles up in response to exercise.

Protein in Human Hair Shows Promise for Regenerating Nerves
A protein found in human hair shows promise for promoting the regeneration of nerve tissue and could lead to a new treatment option when nerves are cut or crushed from trauma.

Researchers Use Magnetism to Target Cells to Animal Arteries
Scientists have used magnetic fields and tiny iron-bearing particles to drive healthy cells to targeted sites in blood vessels.

Pluristem Announces Second Clinical Indication Revascularization Effect After PLX-PAD Therapy
Pluristem Therapeutics Inc. has announced that it has identified a second clinical indication for its proprietary PLX cells and the expansion of its pipeline of PLX products. Pluristem’s PLX-PAD is expected to begin clinical trials in the second half of 2008 in Europe for the treatment of limb ischemia associated with peripheral artery disease (PAD).

Gene Therapy Gets Injured Mice Moving Again
A combination of gene therapy and tissue grafts could offer an improved way to repair ruptured tendons and ligaments, including common sports injuries such as season-ending knee and shoulder problems, according to a new study in mice.

Sangamo BioSciences Initiates Phase 2 Clinical Trial of ZFP Therapeutic in Stem Cell Mobilization
Sangamo BioSciences, Inc. has announced the initiation of a randomized, single-blind, placebo-controlled, multi-center Phase 2 clinical trial in subjects with mild to moderate diabetic neuropathy.

A Dog’s Stem Cell Life
In the race to perfect “regenerative medicine,” stem cell therapy for animals is ahead of treatment for humans because it is not so strictly regulated. It’s not experimental – it’s here.

Japan Researcher Proposes Stem Cell Bank
Creating a bank to store a new type of stem cell produced from donors’ ordinary skin cells could help reduce time and money for treating patients with regenerative medicine in the future.

China Offers Unproven Medical Treatments
Western doctors warn that patients are serving as guinea pigs in a country that isn’t doing the rigorous lab and human tests that are needed to prove a treatment is safe and effective.

China Parents to Sue Over “Tainted” Umbilical Blood
Scores of Shanghai parents are to sue a biotech firm suspected of concealing the fact that their children’s umbilical cord blood, believed to be a likely cure for future blood diseases, was tainted.


Human Embryonic Stem Cell-Derived Dopaminergic Neurons Reverse Functional Deficit in Parkinsonian Rats
The researchers show that human embryonic stem cell-derived dopaminergic neurons survived transplantation to the neurotoxin 6-hydroxydopamine-lesioned rat striatum and, in combination with the cells newly differentiated from their progenitors, contributed to locomotive function recovery at 5 months.


Cell Therapy Business Development Leader
Portland, OR (Invitrogen)

Irvine, CA (Global Biopharmaceutical Company)

Biomedical Equipment Technician
Los Angeles, CA (Cedars-Sinai Medical Center)

Quality Manager
Singapore (Singapore Cord Blood Bank)


Women Donate Eggs for Cheaper IVF
A UK fertility centre has started a scheme offering half-price IVF treatment for women who donate their eggs to research.

United Kingdom MP’s ‘Life-saving’ Cord Blood Bid
An MP is to launch a bid to get doctors to offer parents the option of storing their baby’s umbilical cord blood.

New York Gives $14.5M for Stem Cell Research
State officials announced $14.5 million in grants to medical institutions for stem-cell research, the first allocation of a planned $600 million in aid over 10 years to expand the research in New York.

Industry and Academia Team Up
For the first time in its three-year existence, the state taxpayer-funded stem cell institute is offering grant money to biotechnology companies.

Strong Support For Embryonic Stem Cell Research Declines, Overall Support Remains Stable, Poll Finds
Strong support for human embryonic stem cell research has declined nationwide from 27% in 2005 to 21% in 2007, but overall support has remained stable at about 54%, according to a survey released late last month by Virginia Commonwealth University.


BrainStorm Cell Therapeutics and Rutgers University Join Forces to Identify a Cure for Spinal Cord Injuries via Stem Cell Research
BrainStorm Cell Therapeutics Inc. is pleased to announce that the Company has expanded its collaboration with Rutgers University in an effort to cure spinal cord injuries through BrainStorm’s cutting-edge adult stem cell research.

BioTime Licenses Human Embryonic Stem Cell Technology from the Wisconsin Alumni Research Foundation
BioTime, Inc. announced it has signed a licensing agreement with the Wisconsin Alumni Research Foundation to 173 patents and patent applications filed internationally relating to human embryonic stem cell technology created by James Thomson at the University of Wisconsin-Madison.

The University of Massachusetts Medical School and the Carnegie Institution of Washington Grant Key RNAi Rights to Oxford Biomedica
The University of Massachusetts Medical School and the Carnegie Institution of Washington have announced that they have entered into licensing agreements with Oxford BioMedica that grants the company rights to key RNA interference patent rights.

CryoLife, Trophic Solutions Sign Licensing Deal
CryoLife Inc. has inked a deal with a Wisconsin company to create and market products that aid the cold storage and preservation of internal organs before they are transplanted.

Invitrogen Announces Acquisition of CellzDirect
Invitrogen Corporation has announced it has entered into a definitive agreement to purchase privately-held CellzDirect, Inc., based in Research Triangle Park, North Carolina, in a cash transaction for approximately $57 million.

Southeast Baptist Joins Network of Hospitals Collecting Umbilical Cord Blood
The Texas Cord Blood Bank has formed a new partnership with a San Antonio area hospital to create a third supply of blood from the umbilical cords of newborns.

Lonza Offers New Immune Cell Type for Immunology Research
Lonza Group AG said it is offering a new cell type called Poietics Human Natural Killer Cells to its existing offering of immune cell.

Osiris Therapeutics to Receive Milestone Payment from JCR Pharmaceuticals
The milestone payment was triggered when JCR Pharmaceuticals filed a Clinical Trial Notice to the Pharmaceuticals and Medical Devices Agency in Japan to initiate a clinical trial in patients with Graft vs. Host Disease.

Osiris Therapeutics Regains Worldwide Rights to Cardiovascular Indications for Prochymal(TM)
Osiris Therapeutics, Inc. has announced it has reclaimed sole worldwide rights to cardiovascular indications for Prochymal and terminated its development and commercialization agreement with Boston Scientific Corporation in order to provide Osiris with the flexibility to enter more strategically beneficial relationships.

Advanced Cell Technology Awarded Grant from the NIH
Advanced Cell Technology, Inc. has announced that the National Institute of General Medical Sciences at the National Institutes of Health has awarded the company an SBIR Phase 1 Small Business Grant.

Investment Banker Gives Stanford $20 Million for Stem Cell Work
John Scully, an investment banker at a Mill Valley firm, is giving $20 million to Stanford University for stem cell research.

New Research Institute to Open
An Oregon-based research institute plans to open a 130,000-square-foot campus in Florida, adding to the growing biotech cluster forming in the region.


Notice Regarding the Applicability of the Federal Information Security Management Act to NIH Grantees (NOT-OD-08-032)

Revised Policy on Enhancing Public Access to Archived Publications Resulting from NIH-Funded Research (NOT-OD-08-033)

Application of Emerging Technologies for Cancer Research (R21) (RFA-CA-08-007)


Application of Emerging Technologies for Cancer Research (R33) (RFA-CA-08-008)

Expansion of the National Mesothelioma Virtual Registry and Tissue Bank (U24) (RFA-OH-08-002)


Approved Biological NDA and ANDA Applications – Update

Licensed Products and Establishments List – Update

All new CBER information can be reached from the What’s New page at What’s New Page



Guidance for Industry and Food and Drug Administration Staff; The Review and Inspection of Premarket Approval Applications Under the Bioresearch Monitoring Program; Availability

Guidance for Industry and Food and Drug Administration Staff; The Review and Inspection of Premarket Approval Application Manufacturing Information and Operations; Availability

Requirements for Human Blood and Blood Components Intended for Transfusion or for Further Manufacturing Use; Extension of Comment Period


14th ISCT Annual Meeting

May 17-20, 2008
Downtown Miami, Florida

Abstract Submission and Early Registration Deadline: January 31, 2008

Full details at: http://www.celltherapysociety.org

 Learn more about Cell Therapy News:  Archives  |  Events  |  Update Profile  |  Contact Us