Personalized Medicine through Genomic Analysis and Molecular Diagnostics
March 31, 2008
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UC Irvine Scientists Find New Way to Sort Stem Cells
UC Irvine scientists have found a new way to sort stem cells that should be quicker, easier and more cost-effective than current methods. The technique could in the future expedite therapies for people with conditions ranging from brain and spinal cord damage to Alzheimer’s and Parkinson’s diseases.
“Virgin” Birth Stem Cells May Offer Tissue Bank
Human egg cells can be tweaked to give rise to valued stem cells that match the tissue types of many different groups of people, U.S. and Russian researchers have reported. They said the stem cells they have created from unfertilized human eggs look and act like embryonic stem cells.
Researchers Get Embryonic Stem Cells from Skin
A third team of researchers has found a way to convert an ordinary skin cell into valued embryonic-like stem cells, with the potential to grow batches of cells that can be directed to form any kind of tissue.
Growing Artificial Skin From Hair Roots
There is new hope for patients with chronic wounds: euroderm GmbH and the Fraunhofer Institute for Cell Therapy and Immunology IZI in Leipzig have been granted approval to produce artificial skin from patients’ own cells.
Artificial Blood Vessels Closer
Scientists are a step nearer the creation of tiny artificial blood vessels after growing minuscule tubes out of stem cells in the laboratory.
South Koreans Claim to Create Cloned Pigs Through Stem Cells
The scientists said they had used stem cells extracted from pigs’ bone marrow to obtain cloned embryos, much improving the success rate.
Gene Therapy Can Reduce Long-term Drinking Among Rodents
A proof-of-principle study has found that administering an anti-Aldh2 antisense gene in rodents can curtail their urge to drink.
RNA Therapy Heals Growth Deficiency Disorder in a Live Animal
A team of Vanderbilt researchers has demonstrated for the first time that RNA interference can heal a genetic disorder in a live animal.
Reneuron Says IND Application for Stem Cell Therapy Still on Hold
The company said that while it has addressed most of the substantive issues raised by the US Food and Drug Administration in the original hold letter on its ReN001 therapy, there are a small number of issues that are not yet resolved.
University Hospitals Researchers Initiate Gene Therapy Trial in Patients with Advanced Skin Cancer
Researchers at the Ireland Cancer Center of University Hospitals Case Medical Center are the first in the region to have joined a nationwide clinical trial to evaluate the effectiveness of a gene therapy in patients with advanced melanoma which is aimed to help a patient’s own immune system fight their cancer.
Northwest Biotherapeutics Conducting Ovarian Cancer Clinical Trial With DCVax(R)-L at University of Pennsylvania
Northwest Biotherapeutics, Inc. has announced that a Phase I/II clinical trial in at least 30 patients, using DCVax(R)-L for recurrent ovarian cancer, has begun at The University of Pennsylvania Center for Research on Early Detection and Cure of Ovarian Cancer and the Abramson Cancer Center.
Boy Develops Leukemia After Gene Therapy in UK
A three-year-old “bubble boy” undergoing pioneering gene therapy in London has developed leukemia, marking another setback for the experimental treatment.
Tengion Launches Third Phase 2 Clinical Trial of Regenerated Human Bladder
Tengion, Inc. has announced it is initiating its third Phase 2 multi-center clinical trial of its Neo-Bladder Augment derived from a patient’s own (autologous) cells.
Disgraced South Korean Stem Cell Scientist Seeking to Resume Research
Hwang Woo-suk is part of a team that requested the Health Ministry last week for permission to carry out research on embryonic stem cells using human eggs.
ABSTRACTS, REVIEWS AND SPECIAL REPORTS
HLA Homozygous Stem Cell Lines Derived from Human Parthenogenetic Blastocysts
The researchers report the successful derivation of four stable hpSC-Hhom lines from both HLA homozygous and HLA heterozygous donors.
Unique Dielectric Properties Distinguish Stem Cells and Their Differentiated Progeny
These findings provide evidence for a whole cell property that reflects stem cell fate bias, and establish dielectrophoresis (DEP) as a tool with unique capabilities for interrogating, characterizing, and sorting stem cells.
Cell Therapy Business Development Leader
Portland, OR (Invitrogen)
Irvine, CA (Global Biopharmaceutical Company)
Biomedical Equipment Technician
Los Angeles, CA (Cedars-Sinai Medical Center)
Singapore (Singapore Cord Blood Bank)
Clinical Development Research Associate
Poway, California (VetStem)
Islet Cell Associate Research Director
Irvine, CA (University of California, Irvine)