Fat Kills Cancer: Turning Stem Cells Taken from Fat Tissue into Personalized, Cancer-Targeted Therapeutics
Researchers in Slovakia have been able to derive mesenchymal stem cells from human adipose, or fat, tissue and engineer them into “suicide genes” that seek out and destroy tumors like tiny homing missiles.
Researchers Use Adult Stem Cells to Create Soft Tissue
A Columbia research team aims to create long-lasting soft tissue implants from mesenchymal stem cells harvested from the patient’s own bone marrow or adipose tissue.
Cloned Sperm Created in the Lab
Cloning sperm could enable men with very low sperm counts to become fathers.
Insight into Neural Stem Cells has Implications for Designing Therapies
Scientists have discovered that adult neural stem cells, which exist in the brain throughout life, are not a single, homogeneous group. Instead, they are a diverse group of cells, each capable of giving rise to specific types of neurons.
Opexa Advances Monocyte Derived Islet Technology to Proof of Principle in stz-induced NOD/SCID Mice
Two recent presentations covered research from Opexa’s innovative adult stem cell program regarding the development of adult monocyte-derived islets, as beta-cell replacement therapy for diabetes mellitus.
Stem Cell Transplants from Unrelated Donors Effective for Younger Patients with AML with Adverse Cytogenetics
Researchers affiliated with the International Blood and Marrow Transplant Registry have reported that stem cell transplants from unrelated donors are equally effective for patients with acute myeloid leukemia with favorable, intermediate and unfavorable cytogenetics who were 60 years of age or younger.
Stem Cell Procedure Successfully Treats Amyloidosis Patients
Researchers from the Stem Cell Transplant Program and the Amyloid Treatment and Research Program at Boston University Medical Center (BUMC) have found that tandem cycles of high-dose chemotherapy and blood stem cell transplantation can help treat patients with immunoglobulin-light chain (AL) Amyloidosis who did not respond to initial treatment with this method.
Injectable Filler Product Said to Abolish Anti-ageing Concerns
A suspension of human dermal fibroblasts in cell storage medium, the Vavelta facial rejuvenation product was introduced this week at the UK’s largest medical aesthetic conference.
The Perfect Match: Bone Marrow Donation
New techniques make joining a registry and donating marrow easier and less painful.
FDA Delay In Cancer Therapy Is Attacked
The debate over Provenge illustrates the highly charged atmosphere that often surrounds new treatments as the desperation of deathly ill patients increasingly converges with the high-stakes intensity of biotech investing in the anything-goes forum of the Internet.
Seeking Hope in Chinese Stem Cells
The treatments may not work or even be safe, but dozens make the trek each month.
ABSTRACTS, REVIEWS AND SPECIAL REPORTS
Concise Review: No Breakthroughs for Human Mesenchymal and Embryonic Stem Cell Culture: Conditioned Medium, Feeder Layer, or Feeder-Free; Medium with Fetal Calf Serum, Human Serum, or Enriched Plasma; Serum-Free, Serum Replacement Nonconditioned Medium, or Ad Hoc Formula? All That Glitters Is Not Gold!
Although clinical studies have already started, many questions remain unsolved, and concomitantly even more evidence on suitable and safe off-the-shelf products (mainly xeno-free) for embryonic and mesenchymal stem cells is cropping up, even though there should be no rush to enter the clinical stage while the underlying basic research is still not so solid.
Cancer Vaccines: Moving Beyond Current Paradigms
Although no therapeutic cancer vaccine has to date been approved by the Food and Drug Administration, several new paradigms are emerging from recent clinical findings both in the use of combination therapy approaches and, perhaps more importantly, in clinical trial design and end point analyses