Brain Creates New Nerve Cells
Researchers have discovered a type of brain cell that continuously regenerates in humans.
Adult Stem Cells Decide the Fate of Their Daughters
Researchers found that intestinal stem cells make important decisions about their fate by communicating directly with their daughter cells, instructing them to become one of two possible cell types.
Males More Prone to Cloning
A new study shows that mouse embryos created from male adult cells were more than three times as likely to develop to term as those created from female adult cells.
New Hope For Regenerative Medicine: Hematopoietic Reconstitution With Uniparental Stem Cells
Researchers report on their success in using uniparental embryonic stem cells to replace blood stem cells in mice. Uniparental embryonic stem cells are an appealing alternative source of patient-derived embryonic stem cells, as they have several advantages over embryonic stem cell lines generated by somatic cell nuclear transfer (also known as therapeutic cloning).
Researchers Discover "Sticky" Proteins Fuse Adult Stem Cells to Cardiac Muscle, Repairing Hearts
Cardiologists are increasingly using adult stem cells in clinical trials to repair hearts following heart attacks, but no one has understood how the therapy actually works. Now, in animal experiments, researchers at The University of Texas M. D. Anderson Cancer Center have deconstructed the process, describing how the stem cells fuse with heart muscle cells to create new cells that repopulate the ailing organ.
BrainStorm Cell Therapeutics Initiates Stem Cell Safety Study in Primates for Parkinson’s Disease
The study utilizes BrainStorm’s proprietary adult stem cell technology which has shown efficacy in animal models of Parkinson’s Disease in previous pre-clinical trials. In those studies, human-bone-marrow-derived stem cells were differentiated into astrocyte-like cells (supporting cells) and transplanted into mice and rats brains. The engrafted cells survived, kept their function and significantly improved the motor symptoms of Parkinson’s Disease animal models over a long period of time.
Human Adult Stem Cells Regenerate Muscle
Italian scientists have found human adult stem cells taken from blood vessels can regenerate muscle in a mouse model of muscular dystrophy.
Doctors Try New Techniques To Regrow Human Tissue
Five soldiers at a military base in Texas are about to participate in a remarkable test to see if they can regrow portions of fingers they lost in the war in Iraq. Doctors plan to treat them with a fine powder called extracellular matrix, harvested from pig bladders.
Stem Cell Breakthrough
A first step has been made towards curing muscular dystrophy with stem cells.
Osiris Announces Top-Line Interim Results for Stem Cell Trial for Knee Repair
Osiris Therapeutics, Inc. has announced six-month interim results in its evaluation of CHONDROGEN(TM) for the regeneration of meniscus in the knee. A total of 55 patients were treated in the Phase I/II, double-blind study evaluating the safety and exploratory effectiveness of CHONDROGEN, a preparation of adult stem cells formulated for direct injection into the knee.
Aastrom’s U.S. Clinical Investigator to Report Interim Data on Long Bone Fracture Repair Trial
Aastrom Biosciences, Inc. has announced that 90% of the patients who have completed the 12 months post-treatment follow-up in the Company’s U.S. Phase I/II multi-center clinical trial evaluating the use of Tissue Repair Cells (TRCs) in the treatment of severe long bone fractures had multiple bone bridges, evidence of bone regeneration.
First Patients Undergo Surgery in Northwest Biotherapeutics’ Phase II Brain Cancer Trial
Northwest Biotherapeutics, Inc. has announced that the first two patients in its pivotal Phase II clinical trial have undergone surgery for newly diagnosed Glioblastoma multiforme (GBM), which is the first step in the preparation of the Company’s DCVax(R)-Brain treatment.
Stem Cells Used in Cosmetic Surgery
Scientists in Japan claim to be able to increase the size of a woman’s breasts using fat and stem cells.
Flawed Stem Cell Data Withdrawn
It is one of the best-known stem cell papers in the past five years, describing adult cells that seemed to hold the same promise as embryonic stem cells. Now, following inquiries by New Scientist, some of the data contained within the papers is being questioned.
ABSTRACTS, REVIEWS AND SPECIAL REPORTS
Mice Cloned From Skin Cells
The researchers’ findings reveal skin as a source of readily accessible stem cells, the nuclei of which can be reprogrammed to the pluripotent state by exposure to the cytoplasm of unfertilized oocytes.
Extensive Neuronal Differentiation of Human Neural Stem Cell Grafts in Adult Rat Spinal Cord
This article reveals that restoration of spinal cord circuitry in traumatic and degenerative diseases may be more realistic than previously thought, although major challenges remain, especially with respect to the establishment of neuromuscular connections.