Stem Cell Marker Identified in Head and Neck Cancer
Researchers have found a marker on head and neck tumor cells that indicates which cells are capable of fueling the cancer’s growth. The finding is the first evidence of cancer stem cells in head and neck tumors.
Studies Show Geron’s Stem Cell Therapeutic For Spinal Cord Injury Produces Nerve Growth Factors
Geron Corporation today reported that studies show GRNOPC1, the company’s human embryonic stem cell (hESC)-based oligodendroglial progenitor therapeutic, produces multiple nerve growth factors, proteins that stimulate the survival and regeneration of neurons damaged during spinal cord injury.
Researchers First To Map Gene That Regulates Adult Stem Cell Growth
Researchers genetically mapped a stem cell gene and its protein product.
Brain Stem Cells Against Cancer?
Gliomas are a group of brain tumors where the most common type is also the most aggressive one. Chemotherapy and radiation have little effect on malignant gliomas, and patients survive only about a year after being diagnosed. But research at Lund University in Sweden provides hope that it may be possible in the future to develop stem cells from the brain into a new way to treat gliomas.
Will Synthetically Engineered Immune Cells Stop AIDS?
Twenty years after its introduction, gene therapy still holds great promise as a way to harness the insidious power of viruses such as human immunodeficiency syndrome (HIV). But scientists have yet to solve a vexing problem: developing an efficient transport system that is capable of delivering therapeutic payloads to specific cells.
Genetic Signature Predicts Recurrence of Breast, Prostate and Other Cancers
Researchers working with breast cancer stem cells at the Stanford University School of Medicine have found 186 genes that together can predict the risk of recurrence in breast cancer patients. Additionally, the same genes predict the recurrence of prostate cancer, lung cancer and medulloblastoma, the most common form of childhood brain cancer.
Daughter Cells Generated from Embryonic Stem Cells May Provide a Safer Way to Develop Clinical Stem Cell Therapies
Scientists at the Genome Institute of Singapore and the National University of Singapore have found a way of manipulating embryonic stem cells (ESCs) that could allow stem cells to be produced in a safe and efficient manner for use in clinical treatments.
University of Minnesota Finds Cell in Adult Heart with Embryonic Stem Cell Capability
Researchers at the University of Minnesota have found a cell type in adult rat heart tissue that can make all types of cardiac cells.
Dual Gene Therapy Suppresses Lung Cancer in Preclinical Test
Combination gene therapy delivered in lipid-based nanoparticles drastically reduces the number and size of human non-small cell lung cancer tumors in mice, researchers at The University of Texas M. D. Anderson Cancer Center and the University of Texas Southwestern Medical Center have reported.
Donor Mesenchymal Cell Infusion May Reduce Established Graft-Versus-Host Disease
Researchers affiliated with the European Bone Marrow Transplant Mesenchymal Stem Cell (MSC) expansion group have reported that the infusion of MSC is effective treatment of refractory acute graft-versus-host disease (GVHD) among patients who have received an allogeneic stem cell transplant.
Aastrom Treats Patients in Adult Stem Cell Clinical Trial for Osteonecrosis
Aastrom Biosciences, Inc. today announced that the first two patients have been treated in a pivotal clinical trial utilizing the Company’s Tissue Repair Cells (TRCs) for the treatment of osteonecrosis (also known as avascular necrosis) of the femoral head.
Potential for Adult Stem Cells to Repair Hearts Damaged by Severe Coronary Artery Disease Investigated by Rush Cardiologists
Rush University Medical Center is one of the first medical centers in the country, and currently the only site in Illinois, participating in a novel clinical trial to determine if a subject’s own stem cells can treat a form of severe coronary artery disease.
AnGes MG, Vical to Start Phase III Clinical Trial of Allovectin for Gene Therapy
AnGes MG Inc. and the U.S. based Vical Inc. has announced the start of phase III of their clinical trial of Allovectin-7, a gene therapy treatment drug for progressive melanoma patients. Allovectin was assigned as an orphan drug, and is aiming to monopolize the market after its sales and distribution have been approved.
Dendreon Corporation’s PROVENGE Granted FDA Priority Review For The Treatment Of Asymptomatic, Metastatic, Androgen-Independent Prostate Cancer
Dendreon Corporation today announced that the U.S. Food and Drug Administration (FDA) has accepted for filing and has assigned priority review status to the Company’s Biologics License Application (BLA) for PROVENGE(R) (sipuleucel-T), its investigational active cellular immunotherapy for the treatment of asymptomatic, metastatic, androgen-independent (also known as hormone refractory) prostate cancer.
Stem Cell Transplant for Eye Repair Raises Concern
An international team of ophthalmologists has expressed grave concern over stem cell transplant procedures used by doctors in India and some other countries for preventing blindness.
GenesisBPS Announces The North American Distribution And FDA 510K Clearance Of The SEPAX Cell Separation System For Cord Blood Processing
GenesisBPS has announced that the SEPAX Cell Separation System, developed and manufactured by Biosafe SA has received 510(k) marketing clearance from the U.S. Food and Drug Administration’s Center for Biologics Evaluation & Research (CBER) for use as a cord blood-processing device.
ABSTRACT, REVIEWS AND SPECIAL REPORTS
Multipotent Mesenchymal Stromal Cells in Blood
In this review, current studies and knowledge about peripheral blood-derived multipotent mesenchymal stromal cells are summarized.