Novel Gene Therapy May Lead to Cure in Hemophilia A Patients
A discovery by Medical College of Wisconsin and BloodCenter of Wisconsin researchers in Milwaukee may be a key to a permanent genetic cure for hemophilia A patients, including a subset who do not respond to conventional blood transfusions.
Healing The Heart With Bone Marrow Cells
Researchers at the McEwen Centre for Regenerative Medicine at Toronto General Hospital have discovered the ‘SOS’ distress signal that mobilizes specific heart repair cells from the bone marrow to the injured heart after a heart attack.
Geron Presents New Data That Document Progress in Development of Therapeutic Products from Human Embryonic Stem Cells
Geron Corporation has announced the presentation of new data that document the company’s progress in the development of first-in-class therapeutic products from human embryonic stem cells (hESCs) for the treatment of degenerative diseases.
Tissue Engineering Breakthrough Could Aid Human Fertility
A supportive gel capsule has allowed researchers to mature mouse eggs in the lab, which then went on to produce offspring for the first time.
Stem Cell Transplants Tested as Innovative Therapy for Scleroderma
In a bold attempt to control a disabling and often fatal immune disease called scleroderma, physicians at Duke University Medical Center are leading a national study to test whether stem cell transplants can reconstruct defective immune systems.
Cell Genesys Announces Publication of Encouraging Phase 1/2 Clinical Results For GVAX(R) Immunotherapy for Prostate Cancer in Early Stage Patients Before Receiving Hormone Therapy
Cell Genesys has completed five Phase 1 and Phase 2 clinical trials of GVAX immunotherapy for prostate cancer in approximately 200 patients with various stages of recurrent prostate cancer, and each trial has demonstrated a favorable safety profile.
Epeius Biotechnologies Corporation Initiates Tri-REX Vaccination Protocols For Breast Cancer
Epeius Biotechnologies has announced the opening of a Vaccine-assisted Phase I/II clinical trial for metastatic breast cancer that is refractory to conventional chemotherapy.
Special Protocol Assessment Granted for TroVax
The U.S. Food and Drug Administration (FDA) has granted Oxford BioMedica a special protocol assessment (SPA) agreement for their immunotherapy agent Trovax in the treatment of clear cell renal adenocarcinoma.
Lab Grown Cartilage Fixes Damaged Knees
Knee cartilage injuries can be effectively repaired by tissue engineering and osteoarthritis does not stop the regeneration process.
Stem Cells Contain Immortal DNA
Researchers show for the first time the mechanism that adult muscle stem cells use to protect their DNA from mutations.
Research Shows Stem Cell’s Fate Affected by Surroundings
U.S. scientists found that even when embryonic stem cells are outside the body and in a laboratory dish, the proteins surrounding the developing cells play a major role in what organ the stem cells become.
Researchers Aim to Cut Future Need for Liver Transplants
University of Edinburgh scientists have identified primitive liver cells – possibly dormant from the earliest developmental stage of a human being – which have the potential to mature into different cells types and help repair a failing liver.
Face Transplant Deemed a Success
The patient’s recovery of sensation four months after the surgery has been “excellent” and her psychological progress is good.
ABSTRACTS, REVIEWS & SPECIAL REPORTS
Using Therapeutic Cloning to Fight Human Disease: A Conundrum or Reality?
This article discusses the biological, legislative, and moral restraints that must be overcome to maximize the potential of this therapeutic strategy and to alleviate human disease.
Stem Cells for the Treatment of Neurological Disorders
This article discusses the application of stem cell therapy to the treatment of neurological disorders.
Gene Therapy Progress and Prospects: Cystic Fibrosis
This review summarizes the progress made in cystic fibrosis (CF) gene therapy since October 2002 and comments on the prospects for CF gene therapy over the coming years.