Insulin Secreted by Embryonic Stem Cells Is Derived From External Sources, Concludes a Study in Cloning and Stem Cells
Cultured embryonic stem cells induced to form insulin-producing Islet-like cell clusters–intended to replace the insulin production lost in diabetes–do not produce detectable amounts of new insulin, according to a report in the December 2005 (Volume 7, Number 4) issue of Cloning and Stem Cells.
Molecule Dictates How Stem Cells Travel
The discovery by researchers at the Massachusetts General Hospital Center for Regenerative Medicine and the Harvard Stem Cell Institute may help improve bone marrow stem cell transplantation and the treatment of several blood disorders.
Animal-human Embryos to be Used for Stem Cell Research
Scientists in Scotland are planning to create animal-human embryos cloned from human skin cells and unfertilized rabbit eggs.
Article 1 Article 2
Intense Bone Marrow Transplantation Protocol Not Useful for Severe MS
“The lack of efficacy, together with some serious side effects, does not favor the use of similar rigorous T cell depleting protocols in the future,” senior author Dr. R. Q. Hintzen, from Erasmus Medical Center in Rotterdam, the Netherlands, and colleagues note.
Boosting Stem Cells to Treat Diabetes
For diabetes patients, who can’t produce their own insulin, human stem cell-based transplants that produce insulin would be a major breakthrough.
Stem Cells Used to Correct Sickle Cell
Scientists say they have found a way to use embryonic stem cells to correct the mutation that causes sickle cell disease in mice.
New Jersey Commission Awards $5 Million in Stem Cell Grants
The New Jersey Commission on Science and Technology awarded a total of $5 million through its Stem Cell Research Grant program, available immediately to 17 researchers at university, nonprofit institution and corporate labs in New Jersey.
ABSTRACT, REVIEWS, & SPECIAL REPORTS
Creatine Kinase, a Magnetic Resonance-Detectable Marker Gene for Quantification of Liver-Directed Gene Transfer
Use of the ck reporter would facilitate the clinical translation of gene therapy by providing a nondestructive readout of the level and duration of therapeutic gene expression.
Derivation of Human Embryonic Stem Cells in Defined Conditions
Here we report feeder-independent human ES cell culture that includes protein components solely derived from recombinant sources or purified from human material. We describe the derivation of two new human ES cell lines in these defined culture conditions.
Origin of Insulin Secreted from Islet-Like Cell Clusters Derived from Murine Embryonic Stem Cells
Despite the presence of at least some level of de novo, synthesized insulin in ILCCs, the majority of insulin released by ILCCs was sequestered from the exogenous medium.