REVIEWS |
Therapeutic Opportunities for Manipulating TReg Cells in Autoimmunity and Cancer In this review, the authors discuss insights into the generation of regulatory T (TReg) cells, their involvement in disease and the molecular basis of the dominant tolerance exerted by FOXP3+ TReg cells that could permit their safe and specific manipulation in humans. [Nat Rev Drug Discov] Abstract
Gene Therapy for the Prevention of Vein Graft Disease Researchers review the pathogenesis of vein graft disease and discuss vector delivery strategies and potential molecular targets for its prevention. They summarize the preclinical and clinical literature on gene therapy in vein grafting and discuss additional considerations for future therapies to prevent vein graft disease. [Transl Res] Abstract
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POLICY |
Stem Cell Lawsuit Finally Over The Supreme Court rejected a request to ban U.S.-funded research on human embryonic stem cells (hESCs). The decision brings to an end a long legal battle that has cast a shadow over hESC studies for over three years. [Supreme Court, United States] Press Release
India Unveils Ambitious Science Policy The Indian government adopted a new science, technology, and innovation policy that calls for doubling the investment in science in the next five years and establishing India among the top five nations in output of scientific publications by the end of the decade. [Indian Government, India] Press Release
US Fiscal Deal Leaves Science Vulnerable Law-makers in Washington DC greeted the new year with a frantic deal meant to avert a fiscal crisis. But the bill that passed the Senate and the House keeps researchers on tenterhooks for at least another two months by delaying mandatory spending cuts that could threaten science funding. [US Government, United States] Press Release |
BUSINESS |
BioTime Signs Definitive Agreement with Geron Regarding Stem Cell Assets BioTime, Inc. and its recently formed subsidiary BioTime Acquisition Corporation jointly announced that they have entered into a definitive Asset Contribution Agreement with Geron Corporation to acquire the intellectual property, including patents and patent applications, and other assets related to Geron’s human embryonic stem cell programs consistent with the financial terms outlined in the letter of intent announced on November 15, 2012. [BioTime, Inc.] Press Release
Ethris Announces Research Based Alliance on SNIM® Modified RNA with Shire Ethris GmbH and Shire announced the initiation of a research based alliance focused on the development and commercialization of novel RNA-based therapeutics. [Ethris GmbH] Press Release
Sanford-Burnham Medical Research Institute and Intrexon Corporation Establish Collaboration to Accelerate Stem Cell Research Sanford-Burnham Medical Research Institute and Intrexon Corporation announced a new collaboration to accelerate stem cell research. [Intrexon Corporation] Press Release
Evotec and Apeiron Biologics Announce Collaboration on Cancer Immunotherapy Evotec AG announced that Evotec and Apeiron Biologics have entered into a research collaboration with the objective of developing immunomodulatory lead compounds for the treatment of cancer. [Evotec AG] Press Release
Emory/Georgia Tech Regenerative Engineering and Medicine Center Awards 11 Collaborative Seed Grants The Emory/Georgia Tech Regenerative Engineering and Medicine Center recently awarded 11 seed grants, totaling $630,000, for promising new research in regenerative medicine. The seed grants focus on how the body – including bone, muscle, nerves, blood vessels and tissues – can harness its own potential to heal or regenerate following trauma or disease. [Georgia Institute of Technology] Press Release
Solstice Biologics Secures $18 Million Series A; Licenses RNAi Delivery Technology from UC San Diego Solstice Biologics LLC announced the completion of a $18 million Series A financing led by venBio and joined by Aeris Capital AG. In addition, Solstice has acquired an exclusive license to University of California (UC), San Diego intellectual property covering technology that enables RNA molecules to cross membranes of multiple cell types, a perplexing problem that has been a bottleneck in delivering on the therapeutic potential of RNA interference (RNAi) and microRNA. [PR Newswire Association LLC] Press Release
Soft Tissue Regeneration Receives FDA Clearance to Market Breakthrough Rotator Cuff Repair Device Soft Tissue Regeneration announced that it has received FDA clearance to market its STR GRAFT, a biodegradable scaffold used for soft tissue augmentation and rotator cuff repair. Developed by Cato T. Laurencin, the STR GRAFT is a three-dimensional braided engineered matrix that Laurencin likens to a patch. [PR Newswire Association LLC] Press Release
ThermoGenesis Announces Sale of ThermoLine Product Line to Helmer Scientific ThermoGenesis Corp. announced it has sold its ThermoLine plasma freezer and thawer product line to Helmer Scientific for an undisclosed sum of cash. The acquisition is part of Helmer’s growth strategy and a continuing commitment to providing high quality products to the medical and blood bank community. [ThermoGenesis Corp.] Press Release |
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