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Scientists Identify New Kind of Stem Cell Found in Testes
Scientists at the Stanford School of Medicine and at the University of California San Francisco have succeeded in isolating stem cells from human testes, which bear a striking resemblance to embryonic stem cells.
Single Virus Used to Convert Adult Cells to Embryonic Stem Cell-like Cells
Whitehead Institute researchers have greatly simplified the creation of so-called induced pluripotent stem cells, cutting the number of viruses used in the reprogramming process from four to one.
Patient-Derived Induced Stem Cells Retain Disease Traits
Svendsen and colleagues at UW-Madison and the University of Missouri-Columbia created disease-specific stem cells by genetically reprogramming skin cells from a patient with spinal muscular atrophy.
Hebrew University of Jerusalem-Hadassah Medical Scientists Reveal Mechanism that Triggers Differentiation of Embryo Cells
The mechanism whereby embryonic cells stop being flexible and turn into more mature cells has been discovered by scientists at the Hebrew University of Jerusalem.
Columbia University Scientist Devises New Way to More Rapidly Generate Bone Tissue
Using stem cell lines not typically combined, researchers at Columbia University Medical Center have designed a new way to “grow” bone and other tissues.
Bioreactors Might Solve Blood Blood-Platelet Supply Problems
It might be possible to grow human blood platelets in the laboratory for transfusion, according to a new study at The Ohio State University Medical Center.
Functional Vasculature Generated from Advanced Cell Technology’s Human Embryonic Stem Cells
Advanced Cell Technology, Inc. reported that it is feasible to differentiate human embryonic stem cells into functional human vasculature and that they have the potential for both endothelial cell and vascular smooth muscle cell lineage differentiation.
“Scrawny” Gene Keeps Stem Cells Healthy
Scientists at the Carnegie Institution have identified a gene, named scrawny, that appears to be a key factor in keeping a variety of stem cells in their undifferentiated state.
Molecular Marker Identifies Normal Stem Cells as Intestinal Tumor Source
Scientists at St. Jude Children’s Research Hospital have answered a central question in cancer biology: whether normal stem cells can give rise to tumors.
Stem Cells and Leukemia Battle for Marrow Microenvironment
Learning how leukemia takes over privileged “niches” within the bone marrow is helping researchers develop treatment strategies that could protect healthy blood-forming stem cells and improve the outcomes of bone marrow transplantation for leukemia and other types of cancer.
VIDEO: Fusing Embryonic Stem Cells with Adult Cells Using Highly Efficient New Fusing System
MIT engineers have developed a new, highly efficient way to pair up cells so they can be fused together into a hybrid cell, for example, fusing an adult cell and an embryonic stem cell allows researchers to study the genetic reprogramming that occurs in such hybrids.
Scientists Call Up Stem Cell Troops to Repair the Body Using New Drug Treatments
Scientists have tricked bone marrow into releasing extra adult stem cells into the bloodstream, a technique that they hope could one day be used to repair heart damage or mend a broken bone.
Newly Discovered Esophagus Stem Cells Grow Into Transplantable Tissue
Researchers at the University of Pennsylvania, School of Medicine have discovered stem cells in the esophagus of mice that were able to grow into tissue-like structures and when placed into immune-deficient mice were able to form parts of an esophagus lining.
Scientists Develop Method for Generating Novel Types of Stem Cells
A team led by Scripps Research Institute scientists has for the first time developed a technique for generating novel types of rat and human stem cells with characteristics similar to mouse embryonic stem cells.
Hebrew University of Jerusalem-Hadassah Medical Scientists Succeed Through Stem Cell Therapy in Reversing Brain Birth Defects
Scientists at the Hebrew University of Jerusalem have succeeded in reversing brain birth defects in animal models, using stem cells to replace defective brain cells.
Gene Therapy Reversed Heart Damage in Heart Failure
Long-term gene therapy resulted in improved cardiac function and reversed deterioration of the heart in rats with heart failure, according to a recent study conducted by researchers at Thomas Jefferson University’s Center for Translational Medicine.
Researchers Engineer Pancreatic Cell Transplants To Evade Immune Response
Researchers at Albert Einstein College of Medicine of Yeshiva University have developed a technique for transplanting insulin-producing pancreatic cells that causes only a minimal immune response in recipients.
BioLife Solutions Completes Safety Studies on HypoThermosol(R) and CryoStor(TM)
BioLife Solutions Inc. recently announced that it has completed an initial series of small animal safety studies at the Seattle-based Fred Hutchinson Cancer Research Center on its bio-preservation media products, HypoThermosol and CryoStor.
Neuralstem Files FDA Application for First ALS Stem Cell Trial
Neuralstem, Inc. announced recently that it has filed an Investigational New Drug application with the U.S. Food and Drug Administration to begin a clinical trial to treat amyotrophic lateral sclerosis.
Pluristem Therapeutics Inc. Announces Filing an IMPD to Commence Clinical Trials Utilizing PLX-PAD for Critical Limb Ischemia in Europe
Pluristem Therapeutics Inc. announced recently that it has filed an Investigational Medicinal Product Dossier application with the Paul Ehrlich Institute to begin clinical trials with its placental-derived adherent stromal cell product, termed PLX-PAD, for the treatment of critical limb ischemia.
Medistem Files IND for Endometrial Regenerative Cells in Treatment of Critical Limb Ischemia
Medistem Inc. announced recently it has filed an Investigational New Drug Application with the United States Food and Drug Administration to undertake clinical studies using its proprietary endometrial regenerative cells in patients with an advanced form of peripheral artery disease termed “critical limb ischemia.”
Athersys Receives IND Authorization for Multistem in Treatment of Ischemic Stroke
Athersys, Inc. announced recently that it has received authorization from the U.S. Food and Drug Administration to begin a Phase I clinical trial evaluating the safety of administration of its “off-the-shelf” adult stem cell product, MultiStem(R), in the treatment of ischemic stroke.
StemCells, Inc. Receives FDA Approval to Initiate Clinical Trial of HuCNS-SC Cells in a Myelin Disease
StemCells, Inc. recently announced that it has received approval from the U.S. Food and Drug Administration to initiate a clinical trial of the Company’s proprietary purified human neural stem cell product candidate to treat Pelizaeus-Merzbacher Disease, a fatal brain disorder that mainly affects young children.
Clinical Trial at UC San Diego Medical Center Tests Treatment for Heart Failure with Adult Stem Cells
The University of California, San Diego Medical Center is the first hospital in California to enroll patients in a multi-center clinical trial, sponsored by Angioblast Systems Inc., to examine the safety and feasibility of administering adult stems cells to treat congestive heart failure.
Adipose Stem and Regenerative Cell Clinical Study Underway for Treatment of Chronic Radiation Injury
Cytori announced that the first patient was enrolled in an investigator-initiated study using adipose-derived stem and regenerative cells to treat the chronic effects of radiation-induced local tissue injury.
Drug Provides Enhanced Mobilization of Stem Cells for Autologous Transplantation in Non-Hodgkin’s Lymphoma and Multiple Myeloma Patients
Genzyme Corporation announced recently that the U.S. Food and Drug Administration has granted marketing approval for Mozobil, a drug intended to mobilize hematopoietic stem cells to the bloodstream for collection.
ABSTRACTS, REVIEWS AND SPECIAL REPORTS
Characterization of Human Embryonic Stem Cells with Features of Neoplastic Progression
The researchers in this study characterize two variant hES cell lines that express pluripotency markers at high levels and do not harbor chromosomal abnormalities by standard cytogenetic measures.
Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal During Homeostasis and Repair
Bone marrow hematopoietic stem cells are crucial to maintain lifelong production of all blood cells. Although HSCs divide infrequently, it is thought that the entire HSC pool turns over every few weeks, suggesting that HSCs regularly enter and exit cell cycle.
Crypt Stem Cells as the Cells-of-origin of Intestinal Cancer
This report shows that deletion of Apc in long-lived intestinal stem cells leads to their transformation within days.
Largest Ever Stem Cell ‘Dialogue’ Provides Insight into Public Attitudes
Results of the largest ever public dialogue on stem cell research in the UK have revealed high levels of public support for stem cell science and technology, from basic research to development of treatments.
A Forum for International Leaders
The STEM CELLS CONGRESS
Contributing to the Future of Regenerative Medicine
February 25- 27, 2009 | San Francisco, California
– Address the topics central to the theme of regenerative medicine
– Network with prominent researchers, clinicians, businessmen, and regulators at the cutting edge of their respective fields
– Develop strategies to enable the rapidly expanding therapeutic potential of regenerative medicine
Advance registration Discount Expires Friday, January 23!
Register now and save $200! http://www.TheStemCellsCongress.com
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