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VIDEO: Breakthrough in Cell-Type Analysis Offers New Ways to Study Development and Disease
Researchers at The Rockefeller University have developed a method to reveal translational profiles by isolating the genetic messages that govern protein production in different cell types.
‘Femtomolar Optical Tweezers’ May Enable Sensitive Blood Tests
The National Institute of Standards and Technology has licensed a patented “optical tweezers” technique for detecting and measuring very small concentrations of a biological substance – such as a virus on a surface.
“Jet Injection” for Gene Therapy – First Clinical Trial Evaluates Feasibility
For the first time in a clinical study, researchers have tested a new technology enabling them to transfer genetic material directly into a tumor by means of high pressure.
A*STAR and NUS Researchers Score Breakthrough in Developing Unlimited Number of Pure Insulin-Producing Cells
The researchers found that these pure insulin-producing cells, which according to electron microscopy studies, have the same sub-cellular structures as the insulin-producing cells naturally found in the pancreas, were highly effective in treating diabetes in the mouse model.
Pluripotent Stem Cells Shown to Generate New Retinal Cells Necessary for Vision
Pluripotent stem cells can be converted into the different classes of retinal cells necessary for vision, according to a new study from researchers at Syracuse University of New York Upstate Medical University.
Neurons Derived from Embryonic Stem Cells Restore Muscle Function after Injury
Dalhousie Medical School researchers have discovered that embryonic stem cells may play a critical role in helping people with nerve damage and motor neuron diseases, such as amyotrophic lateral sclerosis, regain muscular strength.
Jefferson Researchers Define Ideal Time for Stem Cell Collection for Parkinson’s Disease Therapy
Researchers have identified a stage during dopamine neuron differentiation that may be an ideal time to collect human embryonic stem cells for transplantation to treat Parkinson’s disease.
First Trial in the U.S. to Treat Both Ischemic & Non-Ischemic Heart Failure to be Performed by University of Utah Researchers Using Patient’s Own Stem Cells
Researchers at the University of Utah are enrolling people in a new clinical trial that will look at the safety of injecting Cardiac Repair Cells and their ability to improve heart function.
Histogen Announces Start of Hair Regrowth Clinical Evaluation
Histogen, Inc. recently announced the start of the Company’s first human clinical evaluation to evaluate the safety in the clinical application of the ReGenica product.
Aastrom Announces Treatment of First Patient in U.S. Phase II IMPACT-DCM Trial
The U.S. Phase II clinical trial is designed to evaluate the surgical delivery of the Company’s Cardiac Repair Cells directly into human heart muscle for the treatment of dilated cardiomyopathy, a severe form of chronic heart failure.
ABSTRACTS, REVIEWS AND SPECIAL REPORTS
Hepatocyte Growth Factor/c-MET Axis-mediated Tropism of Cord Blood-derived Unrestricted Somatic Stem Cells for Neuronal Injury
An under-agarose chemotaxis assay was used to investigate whether unrestricted somatic stem cells that were recently characterized in human cord blood are attracted by neuronal injury in vitro.
The Na+/H+ Exchanger Isoform 1 Facilitates Cardiomyocyte Embryonic Stem Cell Differentiation
To gain insights into improving cardiomyocyte development from stem cells we examined the role of the Na+/H+ exchanger isoform 1 in cardiomyocyte differentiation.
Novel Cryopreservation Method for Dissociated Human Embryonic Stem Cells in the Presence of a ROCK Inhibitor
One of the major challenges regarding the application of human embryonic stem cells is the development of an efficient cryopreservation protocol, since current methods, which include slow-freezing–rapid thawing and vitrification of colonies in suspension, present poor viability and high differentiation rates.
Transplanted Mouse Embryonic Stem-Cell-Derived Motoneurons Form Functional Motor Units and Reduce Muscle Atrophy
In this study, the researchers ask whether transplanted embryonic stem cells differentiated into motor neurons can form functional synapses with host muscle, and if so what effects do they have on the muscle.
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