Scientists Identify Genes Capable of Regulating Stem Cell Function
Scientists from The Forsyth Institute, Boston, MA, and the Howard Hughes Medical Institute at the University of Utah School of Medicine have developed a new system in which to study known mammalian adult stem cell disorders.
University of North Carolina Scientists Turn Human Skin Cells into Insulin-Producing Cells
Researchers at the University of North Carolina at Chapel Hill School of Medicine have transformed cells from human skin into cells that produce insulin, the hormone used to treat diabetes.
The Derivation of Human Embryonic Stem Cells Without Deleting the Embryo
Scientists at UZ Brussel have for the first time succeeded in deriving human embryonic stem cells from one single cell of a four-cell embryo on day 2 of its pre-implantation development.
Researchers Disclose Key Advance in Treating Spinal Cord Injuries
Researchers in Rochester, NY and Colorado have shown that manipulating stem cells prior to transplantation may hold the key to overcoming a critical obstacle to using stem cell technology to repair spinal cord injuries.
Seeing the Shape of Gene Silencing
Researchers have devised clever new techniques to mimic the chemical marks on tightly wound DNA-protein complexes that silence gene expression.
Children’s Hospital of Pittsburgh of UPMC Researchers Identify Genetic Mutation That May Predict Organ Rejection
Using a novel combination of cutting-edge technologies to scan the human genome, researchers at Children’s Hospital of Pittsburgh of UPMC have identified a genetic mutation that identifies transplant recipients who experience rejection.
Singapore Scientists’ Discovery on Stem Cell Factors Proves a Significant Step for Stem Cell Technology and Clinical Research
Singapore scientists have recently made a significant discovery in understanding the behaviour of a class of gene regulators, known as transcriptional factors, paving the way for important advancements in stem cell technology and clinical research.
Muscle Stem Cell Identity Confirmed by Stanford Researchers
A single cell can repopulate damaged skeletal muscle in mice, say scientists at the Stanford University School of Medicine, who devised a way to track the cell’s fate in living animals.
‘Baby’ Fat Cells May be Key to Treating Obesity
Immature, or “baby,” fat cells lurk in the walls of the blood vessels that nourish fatty tissue, just waiting for excess calories to help them grow into the adult monsters responsible for packing on the extra pounds, researchers at UT Southwestern Medical Center have found in mice.
Pluristem Presents Final PLX-PAD Efficacy Data Supporting Upcoming IND Submission to the U.S. FDA
Pluristem Therapeutics Inc. announced recently the successful conclusion of its pre-clinical efficacy studies utilizing PLX-PAD prior to the initiation of human clinical trials.
Inovio Biomedical Achieves 75% Complete Response Rate in Preclinical Testing of DNA-Based Cancer Vaccine Using Its Electroporation DNA Delivery System
Inovio Biomedical Corporation announced recently that it achieved positive results from its proprietary research and development program for DNA-based cancer vaccines delivered using the company’s electroporation-based DNA delivery technology.
Engineered Stem Cells Carry Promising Amyotrophic Lateral Sclerosis Therapy
Using adult stem cells from bone marrow as “Trojan horses” to deliver a nurturing growth factor to atrophied muscles, Wisconsin scientists have successfully slowed the progression of ALS in rats.
ABSTRACTS, REVIEWS AND SPECIAL REPORTS
ES-Cell Derived Hematopoietic Cells Induce Transplantation Tolerance
The researcher’s data show, for the first time, the efficacy of ES-derived CD45+ HPCs to engraft in allogenic recipients without the use of immunosuppressive agents, there by protecting cardiac allografts from rejection.
Stem/Progenitor Cells from Bone Marrow Decrease Neuronal Death in Global Ischemia by Modulation of Inflammatory/Immune Responses
The human mesenchymal stromal cells injected into the hippocampus both improved neurologic function and markedly decreased neuronal cell death of the hippocampus.
Stem Cells for Kidney Repair: Useful Tool for Acute Renal Failure?
Chen et al. report that local mesenchymal stem cells derived from adult mouse kidneys are another source of cells that can differentiate into mature kidney cells that may participate in renal repair after systemic administration.
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