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Scientists at UCLA Reprogram Human Skin Cells into Embryonic Stem Cells
UCLA stem cell scientists have reprogrammed human skin cells into cells with the same unlimited properties as embryonic stem cells, without using embryos or eggs.
Functional Immune System Can Be Derived From Embryonic Stem Cells
A new study demonstrates for the first time that embryonic stem cells can be used to create functional immune system blood cells, a finding which is an important step in the utilization of embryonic stem cells as an alternative source of cells for bone marrow transplantation.
Plucking Cells out of the Bloodstream
A new implantable device can extract stem cells for therapeutic transplant or program cancer cells to die.
Scientists Solve Gene Therapy Mystery
The University of Glasgow team, in collaboration with colleagues at University College London and the Medical Research Council Clinical Sciences Centre, worked with adenoviruses, a class of virus that cause respiratory, intestinal, and eye infections in humans. They were then mutated to allow them to be used in the gene therapy treatment.
Vaccine Protects Against Prostate Cancer in Mice
An experimental vaccine can provide long-term protection against prostate cancer in mice genetically predisposed to the disease, new research indicates.
Transplanted Liver Lining Cells May Cure Hemophilia
Scientists have shown that transplanting healthy liver cells into mice with hemophilia enables the animals to produce a critical clotting factor missing in humans with type A hemophilia.
Human Stem Cell Tests Could Be Near
Geron CEO plans embryonic stem cell tests in humans this spring if the biotech meets the FDA’s ‘high bar.’
Pioneering New Islet Transplantation for Patients with Type 1 Diabetes
A team led by Dr Richard Smith, Consultant Senior Lecturer in Renal Medicine at North Bristol NHS Trust and the University of Bristol, will offer a pioneering new treatment for some patients with Type 1 diabetes.
HepaLife’s Bioartificial Liver Dramatically Reduces Toxic Marker for Acute Liver Failure
HepaLife Technologies, Inc. has announced important, positive results from new in-vitro studies in which the Company’s patented PICM-19 liver stem cells were placed inside its proprietary bioartificial liver device and were able to successfully and quickly remove high levels of toxic ammonia within a very short period of time.
Highly Successful Results of Bone Repair Trial Show that Mesoblast’s Stem Cells Promote and Repair Fracture Healing
Mesoblast Limited has announced highly successful results from its clinical trial at The Royal Melbourne Hospital in 10 patients suffering from non-healing, long bone fractures of the legs.
Gene Therapy Protocol at UCSD Activates Immune System in Patients with Leukemia
A research team at the Rebecca and John Moores UCSD Cancer Center at University of California, San Diego reports that patients with chronic lymphocytic leukemia who were treated with a gene therapy protocol began making antibodies that reacted against their own leukemia cells.
Diamyd Medical Receives FDA Approval to Initiate Clinical Study in Chronic Pain
Diamyd Medical has announced that it has received approval from the U.S. FDA to initiate a Phase I study in chronic pain using NP2, the company’s first drug candidate in its Nerve Targeting Drug Delivery System gene therapy platform.
Cell Genesys Reports Association Between Immune Response and Patient Survival in Phase 2 Trial of GVAX Immunotherapy for Prostate Cancer
Cell Genesys, Inc. reports the results of an analysis examining the potential association between immune responses to GVAX immunotherapy for prostate cancer and increased patient survival in a Phase 2 trial in patients with metastatic, hormone refractory prostate cancer.
Polyplus Gene Delivery Tool Poised for Phase II
A Phase II clinical trial using French company Polyplus-transfection’s innovative gene delivery tool, in vivo-jetPEI, is set to go ahead this month in Europe and the US.
Dendreon Will Have to Wait for FDA
A congressional committee said Wednesday that it would not hold a hearing to investigate possile conflicts of interests relating to the FDA’s decision to delay approval of Provenge, a drug developed by Dendreon Corp. of Seattle.
ABSTRACTS, REVIEWS AND SPECIAL REPORTS
Stem Cells: In Search of Common Ground
With the number of stem-cell lines rapidly increasing, technology developers are working to improve systems for culturing and efficient differentiation – all with an eye on the clinic.
Concise Review: Isolation and Characterization of Cells from Human Term Placenta: Outcome of the First International Workshop on Placenta Derived Stem Cells
The aim of this review is to summarize and provide the state of the art of research in this field, addressing aspects such as cell isolation protocols and characteristics of these cells, as well as providing preliminary indications of the possibilities for use of these cells in future clinical applications.
Cell Therapy Business Development Leader
Portland, OR (Invitrogen)
Irvine, CA (Global Biopharmaceutical Company)
Biomedical Equipment Technician
Los Angeles, CA (Cedars-Sinai Medical Center)
Singapore (Singapore Cord Blood Bank)