Personalized Medicine through Genomic Analysis and Molecular Diagnostics
March 31, 2008
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The Guts of a Cell, Frozen in Time
A novel 3-D imaging technique provides a first look at the internal structure of human skin cells.
Stanford Researchers Identify Granddaddy of Human Blood Cells
Researchers at the Stanford University School of Medicine have isolated a human blood cell that represents the great-grandparent of all the cells of the blood, a finding that could lead to new treatments for blood cancers and other blood diseases.
Scientists Overcome Obstacles to Stem Cell Heart Repair
Scientists funded by the Biotechnology and Biological Sciences Research Council at Imperial College London have overcome two significant obstacles on the road to harnessing stem cells to build patches for damaged hearts.
Transplanted Bone Marrow Cells Aid Nerve Regeneration
Transplanted bone marrow cells containing adult stem cells can help regenerate damaged nerves, say Japanese researchers.
Adipose-Derived Stem & Regenerative Cells Improve Fat Graft Retention in Preclinical Study
Cytori Therapeutics, Inc. reported positive preclinical results demonstrating adipose-derived stem and regenerative cells improved the quality and long-term retention of a fat graft, representing a potential new approach in reconstructive surgery.
Genitope Corporation Presents New Data On Its Therapeutic Monoclonal Antibodies To Potentially Treat B-Cell Malignancies
Genitope Corporation has announced results of two pre-clinical studies, which demonstrated the proof of concept of the company’s monoclonal antibody program to treat B-cell malignancies such as non-Hodgkin’s lymphoma.
MicroIslet Holds Positive Pre-IND Meeting for US Based Human Clinical Trial With FDA
MicroIslet, Inc. announced that it has met with the U.S. Food and Drug Administration to discuss requirements for the filing of an Investigational New Drug application for MicroIslet-P(TM), a microencapsulated suspension of pancreatic islet cells.
Ireland Cancer Center Researchers Advance Stem Cell Gene Therapy
Ireland Cancer Center of University Hospitals Case Medical Center researchers have recently made great strides in stem cell gene therapy research by transferring a new gene to cancer patients, via their own stem cells, with the ultimate goal of being able to use stronger chemotherapy treatment with less severe side effects.
AVAX Technologies Announces Successful Completion of Phase I/II Study of MVax(R) in Patients with Stage 3 and 4 Melanoma
AVAX Technologies, Inc. has announced the completion of its Phase I/II study for the treatment of patients with melanoma.
Ultrasound for Open Leg Ulcers
For skin transplants to "take root", it needs to be ensured that the patient’s tissue is properly irrigated with blood. Low-frequency ultrasound can promote this effect. Researchers have developed the first device that permits variable control of the ultrasound frequency.
Adipose-Derived Stem Cells Show Promise in Breast Reconstruction
Cytori Therapeutics received results from an independent, investigator-sponsored study in Japan in which adipose tissue-derived stem and regenerative cells were used for breast reconstruction following partial mastectomy.
Neurologix Gene Therapy Approach to Parkinson’s Disease Granted Fast Track Designation From FDA
Neurologix, Inc. has announced that the U.S. Food and Drug Administration has granted Fast Track Designation for the company’s experimental gene transfer procedure for the treatment of advanced Parkinson’s disease.
Osiris Therapeutics Receives FDA Fast Track Status for Prochymal(TM) as First-Line Treatment for Acute GvHD
Osiris Therapeutics, Inc. has announced that Prochymal(TM) has received Fast Track designation from the U.S. Food and Drug Administration, expediting development of the stem cell therapy as a first-line agent for acute Graft versus Host Disease.
Osiris Therapeutics Reports Positive Results for Prochymal(TM) as a Rescue Agent in Pediatric Patients with End-Stage Graft vs. Host Disease
Complete disease resolution was achieved in 58% of children receiving Prochymal as rescue agent for severe treatment resistant GvHD, resulting in a four fold improvement in 100 day survival.
Oxford BioMedica Initiates Phase I/II Trial of ProSavin(R) Gene-Based Treatment for Parkinson’s Disease
Oxford BioMedica has announced that it has initiated a Phase I/II trial of ProSavin, its novel gene-based treatment for Parkinson’s disease.
Oxford Biomedica Announces Data Safety Monitoring Board Recommendation to Continue Trovax Phase III Trial in Renal Cancer
Oxford BioMedica has announced that the independent Data Safety Monitoring Board (DSMB) for the Phase III TRIST study of TroVax in renal cancer has completed its second planned interim analysis. The DSMB concluded that the trial should continue as planned without modification.
Umbilical Cord Blood Can Help Metabolic Disorders
Umbilical cord blood transplants, even from unrelated donors, can help save the lives of babies born with certain inherited metabolic disorders, U.S. researchers reported on Monday.
Cytori Therapeutics Receives FDA 510(k) Clearance for the Cytori Fat Transfer System
This system may be used to harvest, filter, and transfer a patient’s own adipose tissue from one part of a patient’s body to another at the point-of-care in the same surgical procedure.
South Korean Officials Visit Cell Bank
South Korean officials trying to rebuild stem cell research in their country after a scandal involving a top scientist are turning to leading U.S. researchers for guidance.
Face-Transplant Patient ‘Satisfied’
A French woman who two years ago became the first person to receive a face transplant has recovered with remarkably good aesthetic results and has gradually regained normal skin sensation and control of her facial muscles.
ABSTRACTS, REVIEWS AND SPECIAL REPORTS
Restoration of Human Dystrophin Following Transplantation of Exon-Skipping-Engineered DMD Patient Stem Cells into Dystrophic Mice
These data demonstrate that autologous engrafting of blood or muscle-derived CD133+ cells, previously genetically modified to reexpress a functional dystrophin, represents a promising approach for duchenne muscular dystrophy.
Irvine, CA (Global Biopharmaceutical Company)
Biomedical Equipment Technician
Los Angeles, CA (Cedars-Sinai Medical Center)
Singapore (Singapore Cord Blood Bank)
Clinical Development Research Associate
Poway, California (VetStem)
Islet Cell Associate Research Director
Irvine, CA (University of California, Irvine)