Scientists Move Closer To Bio-engineered Bladders
Researchers at the University of York are using an understanding of the special cells that line the bladder to develop ways of restoring continence to patients with serious bladder conditions, including cancer.
Not All Embryonic Stem Cell Lines Are Created Equal
When it comes to generating neurons, researchers have found that not all embryonic stem cell lines are equal.
UCLA Scientists Produce Functioning Neurons from Human Embryonic Stem Cells
Scientists with the Institute of Stem Cell Biology and Medicine at UCLA were able to produce from human embryonic stem cells a highly pure, large quantity of functioning neurons that will allow them to create models of and study diseases such as Alzheimer’s, Parkinson’s, prefrontal dementia and schizophrenia.
Mechanism Discovered In Adult Stem Cell Regulation
Forsyth Institute scientists have discovered an important mechanism for controlling the behavior of adult stem cells.
Proteins Linked To Stem Cells Could Lead To Alzheimer’s Treatment
Researchers combined a technique for transplanting stem cells into rats and a newly discovered compound, phenserine.
GammaCan Receives FDA Orphan Drug Designation for Lead Product VitiGam(TM) for Stage IIB to Stage IV Melanoma
GammaCan anticipates filing an IND with the FDA for a Phase I/II clinical trial by year-end, and initiate clinical testing of VitiGam(TM) in early 2008.
Treatment Permission Granted for Cancer Therapy in India
The Berlin-based biotechnology company MOLOGEN AG has been informed by its license partner ONCO Life Sciences Pvt. Ltd., India, that the respective authorities have granted treatment permission for MOLOGEN’S cell-based gene therapy.
Stem Cell Transplantation Procedure Results In Long-term Survival For Amyloidosis Patients
Researchers from the Stem Cell Transplant Program and the Amyloid Treatment and Research Program at Boston University Medical Center have found that high-dose chemotherapy and blood stem cell transplantation can result in long-term survival for patients diagnosed with primary systemic light chain Amyloidosis.
Death Points to Risks in Research
One woman’s experience in a gene therapy trial highlights weaknesses in the patient safety net.
Targeted Genetics Defends Handling of Fatal Test Case
As more details emerged about the recent death of a patient during a clinical trial conducted by Targeted Genetics of Seattle, the company defended its handling of the case.
Scientists Seek Test To Detect Gene Doping In Athletes
Research under way at the University of Florida could help level the playing field by detecting the first cases of gene doping in professional athletes before the practice enters the mainstream.
Large-animal Clones Reach Fourth Generation
A Japanese geneticist has said his research team created the world’s first fourth-generation cloned pig, an achievement that could help scientists in medical and other research.
ABSTRACTS, REVIEWS AND SPECIAL REPORTS
Directed Differentiation and Transplantation of Human Embryonic Stem Cell-Derived Motoneurons
The researchers present a novel in vitro protocol of the directed differentiation of human embryonic stem cells into engraftable motoneurons.
Complete Spinal Cord Injury Treatment Using Autologous Bone Marrow Cell Transplantation and Bone Marrow Stimulation with Granulocyte Macrophage-Colony Stimulating Factor: Phase I/II Clinical Trial
To assess the safety and therapeutic efficacy of autologous human bone marrow cell transplantation and the administration of granulocyte macrophage-colony stimulating factor, a phase I/II open-label and nonrandomized study was conducted on 35 complete spinal cord injury patients.
Stimulation of Peri-Implant Vascularization with Bone Marrow-Derived Progenitor Cells: Monitoring by In Vivo EPR Oximetry
The researchers developed a cell therapy-type strategy to maintain vascularization around implanted devices using co-administration of bone marrow–derived progenitor cells and demonstrated a novel O2-sensing method to functionally monitor neovascularization in vivo.