Volume 8.30 | Aug 6

Volume 8.30, August 6, 2007
     In this issue: Science | Policy | Business | NIH | CBER | Regulatory
Cell Therapy News on Facebook  Cell Therapy News on Twitter

Top Stories

Stem Cell Therapy Rescues Motor Neurons in ALS Model: In a study that demonstrates the promise of cell-based therapies for diseases that have proved intractable to modern medicine, a team of scientists from the University of Wisconsin-Madison has shown it is possible to rescue the dying neurons characteristic of amyotrophic lateral sclerosis.
Article

Science

New Tissue-engineering Research Focuses On Vocal Cords
Engineering pliable, new vocal cord tissue to replace scarred, rigid tissue in these petite, yet powerful organs is the goal of a new University of Delaware research project.
Article

System To Analyze Beating Heart Stem Cells Could Lead To Heart Attack Treatments
The research, highlighted in the new issue of BBSRC Business, is looking at the process that turns a stem cell into a cardiomyocyte – the beating cell that makes up the heart.
Article

Initial Trigger is Not Enough to Determine a Stem Cell’s Fate
Research uncovering how a signaling pathway regulates stem cell behavior reveals that stem cells, once activated, enter a window of time during which they respond to their environment and retain their ability to alter their developmental path.
Article

Gene That Regulates Blood-forming Fetal Stem Cells Identified
A new University of Michigan study adds to mounting evidence that stem cells in the developing fetus are distinct from both embryonic and adult stem cells.
Article

Imaging Islet Cell Transplants
A new delivery vehicle for the transplanted cells may help overcome rejection, while also allowing clinicians to track the cells once they are inside the body.
Article

Under Magnetic Force, Nanoparticles May Deliver Gene Therapy
The Children’s Hospital of Philadelphia has announced a breakthrough in the method used to deliver gene therapy in an attempt to help blood vessels that have been damaged by artery disease.
Article

Bone Marrow Restores Fertility In Female Mice, Study Confirms
A new study from Massachusetts General Hospital researchers confirms that female mice that receive bone marrow transplantation after fertility-destroying chemotherapy can go on to have successful pregnancies throughout their normal reproductive life.
Article

ImmunoCellular Therapeutics Updates Brain Tumor Vaccine Program Status; First Three Patients Enrolled
The vaccine trial is being conducted at the Johnny L. Cochran, Jr. Brain Tumor Center at Cedars-Sinai Medical Center in Los Angeles.
Article

ThermoGenesis Corp. Obtains FDA Clearance to Market CryoSeal(R) Fibrin Sealant (FS) in Liver Resection Surgeries
ThermoGenesis Corp has announced that the United States Food and Drug Administration has granted clearance for the Company to market the CryoSeal FS System’s autologous fibrin sealant, as an adjunct to hemostasis in liver resection surgery.
Article

Sister-to-sister Transplant Offers Fertility Hope
A previously sterile Belgian woman has successfully received ovarian tissue from her sister in an advance that could offer hope to women with cancer and other women unsuited to normal IVF treatment.
Article

Shamed Scientist’s ‘Breakthrough’
A scientist who faked his research may have actually made a groundbreaking advance – without even realising it.
Article

ABSTRACTS, REVIEWS AND SPECIAL REPORTS

Graft-Versus-Host Disease: A Surge of Developments
The human graft-versus-host reaction continues to both fascinate and frustrate clinical investigation with its lack of predictability, possibly lethal toxicity, but potentially lifesaving anti-tumor effects. Whether new advances will lead to the hoped-for clinical victories will become apparent in the next few years.
Article

Policy

Future of Stem Cell Tests May Hang on Defining Embryo Harm
With the active encouragement of the Bush administration, U.S. scientists in the past year have developed several methods for creating embryonic stem cells without having to destroy human embryos. But some who now wish to test their alternatively derived cells have found themselves stymied by an unexpected barrier: President Bush’s stem cell policy.
Article

Stem Cell Dissent Roils States
Even where voters have moved to support the embryonic research, opposition is fierce.
Article

Even a $400,000 Salary Can’t Woo Stem-Cell Chief to Golden State
Dogged by salary issues – $400,000 appears to be too low – and questions about who is really in charge at the California Institute for Regenerative Medicine, the recruitment effort has missed its ambitious goal of filling the post by June.
Article

Scientists Call For Changes In EU Stem Cell Legislation
Leading stem cell scientists from across Europe are lobbying European government in an attempt to get embryonic stem cell legislation in Europe changed.
Article

United Kingdom MPs Back Human-animal Hybrid Embryos
The creation of human-animal hybrid embryos should be allowed for research, and parents should register donor conception on a child’s birth certificate, a parliamentary committee has said.
Article

Business

Personalized Stem Cell Lines Available Through Leading Fertility Clinics
StemLifeLine announced that under its new partnership agreements, three United States fertility clinics will now offer individuals who have undergone in vitro fertilization the opportunity to use StemLifeLine’s service to develop personal stem cell lines from their unused, stored embryos.
Article

Stem Cell Therapy International Acquires Exclusive Worldwide Rights to New, Anti-Rejection Stem Cell Technology
Stem Cell Therapy International, Inc. has announced that it has acquired the exclusive worldwide rights to a new, U.S. Patent Pending anti-rejection umbilical cord blood stem cell technology.
Article

Advanced Cell Technology Enters Into Definitive Merger Agreement With Mytogen, Inc.
Advanced Cell Technology, Inc. has announced that it has entered into a definitive merger agreement to acquire all of the outstanding capital stock of Mytogen, Inc.
Article

Cytori Therapeutics Expands International Distribution Network for the Celution(TM) System
The four additional distributors will cover Belgium, Greece, Israel, Luxembourg, The Netherlands, and Taiwan.
Article

Alnylam Extends Collaboration on RNAi Research
Alnylam Pharmaceuticals Inc. has extended a collaboration with a major medical device company in a bid to combine an RNAi treatment with a device.
Article

Pressure for Provenge Approval
A prostate cancer patient group has filed a suit, demanding an FDA green light of Dendreon’s vaccine. Investors are on board, too
Article

BrainStorm Cell Therapeutics Completes Restructuring
BrainStorm Cell Therapeutics Inc. is pleased to announce that it has come to a restructured research and license agreement with Ramot at Tel Aviv University with respect to payment obligations for its technology license, and that the Double U Fund, a lender to the Company, has also come to an agreement over funds owed to it by BrainStorm.
Article

Sernova Files Worldwide Patent Application for Innovative Component of Diabetes Cell Therapy
Sernova Corp. is pleased to announce it has filed a patent application for the therapeutic use of adult Sertoli cells.
Article

Medistem Announces Autism Stem Cell Therapy Paper and Filing of IP
Medistem Laboratories, Inc. has announced the filing of IP and publication of a peer reviewed paper describing a novel method of selecting specific subsets of autistic patients for treatment with a combination of cellular therapies.
Article

ThermoGenesis President Named CEO
ThermoGenesis Corp. announced that President and Chief Operating Officer William Osgood has been named chief executive and board member, effective July 30.
Article

Million-pound Injection into Biosciences
The Wellcome Trust, the UK’s largest medical research charity, has awarded almost £1 million to an innovative biosciences company based in Nottingham.
Article

NIH

NIH Offers SBIR Niche Assessment Program to Phase I Awardees (NOT-OD-07-080)
Link

Notice of Release of the NIH/CDC Small Business Innovation Research (SBIR) Contract Solicitation (PHS 2008-1) (NOT-OD-07-081)
Link

NIH Offers Commercialization Assistance Program to SBIR Phase II Awardees (NOT-OD-07-082)
Link

 

Data Ontologies for Biomedical Research (R01) (PAR-07-425)
Link

CBER

Exceptions and Alternative Procedures Approved Under 21 CFR 640.120 – Update
Link

Premarket Approval – CryoSeal FS System – ThermoGenesis Corp
Link

Substantially Equivalent 510(k) Device – AlbaQ-Chek Simulated Whole Blood Controls – Alba Bioscience
Link

Workshop: Licensure of Apheresis Blood Products – Updated Information Regarding On-site Registration
Link

Regulatory

WORLD HEALTH ORGANIZATION (International)

China, India Join WHO Clinical Trial Registry System
China and India have joined the World Health Organization (WHO)’s clinical trial registry system in order to ensure the transparency and good quality of their research activities, the UN agency said on Wednesday.
Article

MEDICINES AND HEALTHCARE PRODUCTS REGULATORY AGENCY (United Kingdom)

Good Laboratory Practice Section Expanded and Restructured
Link

ISCT

7th Annual Somatic Cell Therapy Symposium
September 26-28, 2007
Hyatt Regency Bethesda, Maryland

Registration now open!  Click here to register.

ISCT Membership
Renew your ISCT Membership for 2007 now!
Not a member?  Visit the ISCT website to learn about the benefits of membership.
Link



 Learn more about Cell Therapy News:  Archives  |  Events  |  Update Profile  |  Contact Us