Study Identifies New Gene Therapy Tools for Inherited Blindness
Researchers have taken initial steps toward filling a gap in the toolkit for treating blindness by identifying DNA elements that control when and where genes linked to blindness are turned on.
New Method Of Adult Stem Cell Growth Treats Cornea Disorders
A new method of adult stem cell growth has demonstrated its efficacy for its capacity to grow cornea stem cells.
Pluristem’s PLX Cells Show Promise in Treating Limb Ischemia
Pluristem Life Systems, Inc. has announced that favorable results have been obtained in pre-clinical testing using the Company’s proprietary PLX cells to treat limb ischemia.
Mesoblast Commences Vertebral Disc Cartilage Program to Target Early Disease
Mesoblast Limited has announced that it has commenced preclinical trials of its patented adult stem cell technology for repair and regeneration of vertebral disc cartilage.
Gene Therapy For Parkinson’s Hitches Ride On Virus
A new clinical trial at Oregon Health & Science University is examining whether therapeutic genes that hitch a ride with a harmless virus attracted to nerve cells can reduce Parkinson’s disease symptoms.
Theregen Launches Second Phase One Study of Anginera Cell-Based Patch in Heart Patients
Theregen, Inc. has announced a second Phase I trial to examine the role of its Anginera(TM) cell-based cardiovascular heart patch on adult patients suffering from heart disease.
Acquisitive Ways Paying Off for Genzyme
Last week biotech powerhouse Genzyme announced that a first phase 3 study of stem cell-stimulating drug Mozobil was successful on the primary and secondary efficacy endpoints.
Oxford Biomedica Cleared to Continue Phase III TroVax Cancer Drug Trial
Oxford Biomedica PLC said the independent Data Safety Monitoring Board has concluded that the Phase III trial of its TroVax drug for renal cancer should continue as planned without modification.
Pig To Human Transplantation Getting Closer
Experiments using pigs genetically engineered for compatibility with the human immune system have raised hopes that cross-species transplantation could soon become an option for patients with diabetes and other currently incurable diseases.
China Claims a First with Cloned Rabbit
China has produced the world’s first cloned rabbit using a biological process that takes cells from a fetus.
Back Fractures Common After Stem Cell Transplant
More than one third of children and adolescents who undergo allogenic stem cell transplantation have thinning of their bones, and one in five had crushed vertebrae in their backs, Finnish researchers report.
Authors Retract Science Paper
A lead author is found guilty of misconduct in embryonic cell lineage paper called into question over a year ago.
ABSTRACTS, REVIEWS AND SPECIAL REPORTS
Hematopoietic Stem Cell Transplantation in Multiple Myeloma
Newer and better induction regimens, rigorous analysis of results with autologous and allogeneic transplantation, and the development of risk-adapted stratification provide the impetus for this critical evaluation of the role of hematopoietic stem cell transplantation in multiple myeloma.
Aging Hematopoietic Stem Cells Decline in Function and Exhibit Epigenetic Dysregulation
In highly purified hematopoietic stem cells from mice aged 2 to 21 months, gene expression analysis indicates a deficit in function yet an increase in stem cell number with advancing age.