Stem Cells Provide Clues To Cancer Spread
The University of Manchester study used embryonic stem cells to investigate how some tumours are able to migrate to other parts of the body, which makes the treatment of cancer much more difficult.
Bone Marrow Stem Cells Mimic Cancer but Do Not Initiate It
Researchers found that bone marrow stem cells attracted to the site of a cancerous growth frequently take on the outward appearance of the malignant cells but don’t actually seed cancer.
Cord Blood Stem Cells Produce Insulin
Stem cells taken from the umbilical cords of newborns can be engineered to produce insulin and may someday be used to treat diabetes.
Gene Therapy Helps Arthritis Pain, Damage in Mice
A gene therapy treatment that helped make cells more sensitive to the body’s own painkillers not only helped ease arthritis pain in mice but also reduced other symptoms.
Genzyme’s Gene Therapy Shows Promise
Genzyme has announced that its gene-therapy technique helped preserve brain function and extend lifespan in mice with the equivalent of Niemann-Pick disease, a metabolic illness that in some forms can be fatal in infancy.
Jefferson Scientists Use Gene Therapy to Reverse Heart Failure in Animals
Heart researchers at the Center for Translational Medicine at Jefferson Medical College have used gene therapy to reverse heart failure in animals.
Muscle Stem Cells Effectively Treat Urinary Incontinence Long Term
Women with stress urinary incontinence treated using muscle-derived stem cell injections to strengthen their sphincter muscles experience long-term improvements in their condition. The study, which followed patients for more than one year, suggests that the approach is safe, improves patients’ quality of life and may be an effective treatment for SUI.
Mayo Researchers Study Islet Cell Autotransplantation to Improve Diabetes after Partial Pancreas Removal
Mayo Clinic’s initial experience with pancreatic islet autotransplantation in select patients undergoing partial pancreas removal has found that the procedure shows promise for reducing the effects of pancreatogenic diabetes.
Genitope Corporation Initiates Phase 2 Clinical Trial to Evaluate Use of MyVax Personalized Immunotherapy Following Treatment With Rituximab and Chemotherapy for Follicular Non-Hodgkin’s Lymphoma
MyVax(R) personalized immunotherapy is based on the unique genetic makeup of a patient’s own tumor and is designed to activate the patient’s immune system to fight cancer.
Oncophage(R) Cancer Vaccine Significantly Prolongs Recurrence-Free Survival by 45 Percent in Patients With Intermediate-Risk Kidney Cancer
The end-of-study results showed that in a substantial subset of patients at intermediate risk for disease recurrence, Oncophage demonstrated a clinically significant improvement in recurrence-free survival of approximately 45 percent.
Patient’s Own Platelets May Speed Up Skin Wound Healing
Researchers have looked at how quickly skin wounds treated with a gel of their own platelets compared with a control antibiotic ointment.
Number of China’s Stem Cell Donors Doubles in a Year
The number of stem cell donors in China has nearly doubled over the past year after a promotion campaign by the Red Cross Society of China.
Prostate Cancer Advocates Unite to Fight for Immediate FDA Approval of First-of-Its-Kind Cancer Vaccine
Patients, survivors, physicians and caregivers have formed a coalition called ProvengeNow to fight the recent decision by the U.S. Food and Drug Administration to delay the approval of a new and safe immunotherapy vaccine treatment, until more data becomes available in 2010.
ABSTRACTS, REVIEWS AND SPECIAL REPORTS
Restoration of Cone Vision in a Mouse Model of Achromatopsia
Using adeno-associated virus (AAV) gene therapy, the researchers show that it is possible to target cones and rescue both the cone-mediated electroretinogram response and visual acuity in the Gnat2 cpfl3 mouse model of achromatopsia.
Directed Engineering of Umbilical Cord Blood Stem Cells to Produce C-peptide and Insulin
The researchers demonstrate that human umbilical cord blood-derived stem cells can be engineered to engage in de novo synthesis of insulin.