Growing Nerve Cells in 3-D Dramatically Affects Gene Expression
Nerve cells grown in three-dimensional environments deploy hundreds of different genes compared with cells grown in standard two-dimensional petri dishes.
Effort To Develop Patient-specific Stem Cell Lines Launched
UC Irvine neurobiologist Hans Keirstead and his research team recently launched a project to develop stem cell lines that genetically match human patients.
Gene Therapy Holds Out Hope for Baldness Cure
Skin cells have been primed to regrow hair follicles for the first time and leading scientists claim it is a breakthrough in the quest for a cure for baldness.
Bone Marrow Stem Cells May Cure Eye Disease
Scientists have completed a study using mice which showed that bone marrow stem cells can switch roles and produce keratocan, a natural protein involved in the growth of the cornea – the transparent, outer layer of the eyeball.
New Gene Therapy Targets Cholesterol
The latest technology promising to regulate gene expression has been used therapeutically for the first time – if only in mice – to cut cholesterol levels.
Celladon and Targeted Genetics Initiate Phase I Clinical Trial of MYDICAR(TM) in Patients With Heart Failure
MYDICAR(TM) utilizes an adeno-associated virus (AAV) vector to deliver the SERCA2a gene to heart muscle tissue.
Opexa Therapeutics Completes Patient Enrollment in Phase IIb Trial of Tovaxin(TM) for Treatment of Multiple Sclerosis
Opexa Therapeutics, Inc. has announced the completion of patient enrollment in a 150-patient Phase IIb safety and efficacy study. The trial design is a U.S. multicenter, randomized, double-blind, placebo-controlled study of subcutaneous Tovaxin(TM) in subjects with Clinically Isolated Syndrome (CIS) or Relapsing/Remitting Multiple Sclerosis (RRMS).
For Sale: Stem Cell Enhancers
A California company is marketing the latest in dietary supplements, an extract from algae they claim will boost the number of circulating stem cells, easing disease and discomfort.
ABSTRACTS, REVIEWS AND SPECIAL REPORTS
Generation of Insulin-producing Islet-like Clusters from Human Embryonic Stem Cells
The researchers report here the development of a novel serum-free protocol to generate insulin-producing islet-like clusters (ILCs) from hESCs grown under feeder-free conditions.
Directed Sibling Cord Blood Banking for Transplantation: The Ten Year Experience in the National Blood Service in England
This paper summarises the experience in collection, testing, storage and transplantation of DCB units by the National Blood Service for England and North Wales over ten years.