Cryo-Cell Isolates Maternal Stem Cell With New Therapeutic Potential for Advancing Women’s Healthcare
Researchers at Cryo-Cell International Inc. have isolated a new type of adult stem cell with potential for treating a broad range of diseases in the future. The stem cell, called a maternal placental stem cell, is taken from the discarded placental tissue immediately after childbirth and is maternal in origin.
Students Invent Protective Pouch to Enhance Cell Therapy
Johns Hopkins undergraduates have invented a device to improve cell therapy for diabetes patients by anchoring transplanted insulin-producing cells inside a major blood vessel.
Master Regulatory Gene of Epithelial Stem Cells Identified
This master regulator of epithelial stem cells turns out to be the p63 gene, a close relative to the well-known tumor-suppressing p53 gene. Without p63, mutant mice run out of the regenerative epithelial stem cells.
New Technique Dissects Stem Cells’ Picky Likes, Dislikes
Researchers have described a system that can quickly and systemically screen hundreds of individual molecules for their ability to influence stem cell fates.
Clinical Study Finds BioE’s PrepaCyte-CB Significantly Improves Cell Recoveries from Cord Blood
BioE(R), Inc. has announced its PrepaCyte(TR)-CB Umbilical Cord Blood Processing System significantly improves the recovery of therapeutically important total nucleated cells and white blood cells from human umbilical cord blood when compared to traditional hetastarch-based cord blood processing methods, according to the results of a multi-site, comparative, in-vitro clinical study.
Grant Awarded for Stem Cell Therapy
The Queensland government is getting behind a project aimed at easing the development of stem cell therapies through the use of synthetic materials.
The Stem Cells That Weren’t There: Surprising Finding May Lead To New Diabetes Treatments
Diabetes researchers, investigating how the body supplies itself with insulin, discovered to their surprise that adult stem cells, which they expected to play a crucial role in the process, were nowhere to be found.
Tissue Engineered Scaffolding Allows Reproduction Of Cartilage Tissue
A new study examines the use of tissue-engineered scaffolding made of cartilage cells, which have a limited ability to heal naturally, to replace defective cartilage tissue.
Columbia Researchers Repair Heart Damage in Mice By Activating Gene to Make Adult Heart Stem Cells Regenerate
Adult heart cells usually lack the ability to regenerate, preventing the heart from repairing itself after a heart attack. But in a recent study, Columbia researchers have successfully turned on a gene in adult mice that makes stem cells in the heart divide and allows them to repair potentially deadly heart damage.
CureDuchenne Funds Dr. Giulio Cossu’s Adult Stem Cell Study
CureDuchenne will sponsor a one-year research program that will validate Dr. Giulio Cossu’s stem cell research under GMP conditions. Dr. Cossu’s long-term objective is to conduct phase I/II clinical trials in Duchenne muscular dystrophy pediatric patients with this novel cell therapy protocol based on intra-arterial delivery of donor mesoangioblasts.
Embryonic Stem Cells Trial on Track to Start
The first clinical trial of embryonic stem cells is on track to start early next year on patients with spinal cord injury. Geron will carry out the study on accident victims in six trauma centres across the US.
Surgeons Hail Bone Stem Cell Breakthrough
Fifteen patients have so-far been treated in a ground-breaking clinical trial at the Robert Jones and Agnes Hunt Orthopaedic Hospital in Oswestry.
Amorcyte Cardiac Cell Therapy Trial Completes Second of Four Phases
Amorcyte, Inc. has announced the completion of the second of four dose cohorts in its phase I clinical trial.
Experts to Train Immune Cells to Kill Nose Cancer
Scientists in Hong Kong and Australia will soon test an experimental treatment for nose and throat cancer which “trains” the patient’s own white blood cells to fight the disease.
Phase I Trial for ImmunoCellular Therapeutics Brain Tumor Vaccine Commences
The vaccine trial, which is being conducted at the newly dedicated Johnny L. Cochran, Jr. Brain Tumor Center at Cedars-Sinai Medical Center in Los Angeles, is designed to evaluate safety/toxicity, feasibility and biological activity.
Cell Genesys Provides Update On Clinical Program For GVAX Immunotherapy For Leukemia
Cell Genesys, Inc. has reported that three new clinical trials for GVAX immunotherapy for leukemia are now under way. The new trials are based on encouraging results in an initial Phase 2 study of the product in patients with chronic myelogenous leukemia.
ABSTRACTS, REVIEWS AND SPECIAL REPORTS
Generating Neuron-like Cells from BM-derived Mesenchymal Stromal Cells In Vitro
The researchers investigated the efficacy of different growth factors in inducing MSC differentiation into neurons.
Generation of Functional Hemangioblasts from Human Embryonic Stem Cells
The researchers describe an efficient and reproducible method for generating large numbers of bipotential progenitors—known as hemangioblasts—from human embryonic stem (hES) cells using an in vitro differentiation system. Injection of the cells also reduced the mortality rate after myocardial infarction and restored blood flow in hind limb ischemia in mouse models.