Mouse Stem Cell Line Advance Suggests Potential For IVF-incompetent Eggs
Researchers have found that mouse oocytes that fail to become fertilized during in vitro fertilization are nevertheless often capable of succeeding as “cytoplasmic donors” during a subsequent cloning step using so-called nuclear transfer.
How Stem Cells Are Regulated
Researchers from Biotech Research & Innovation Centre (BRIC) at University of Copenhagen have identified a new group of proteins that regulate the function of stem cells.
Xie Lab Demonstrates the Role of MicroRNA Pathway in Self-Renewal of Germline Stem Cells
Ting Xie, Ph.D., Associate Investigator, and Zhigang Jin, Ph.D., Postdoctoral Research Associate in the Xie Lab, have published results showing that the microRNA pathway is essential for controlling self-renewal of germline stem cells and somatic stem cells in the Drosophila ovary.
Lab-grown Replacement Teeth Fill the Gap
A Japanese team has successfully grown replacement teeth and implanted them into the mouths of adult mice, suggesting that a similar technique could replace missing teeth in humans.
New Way to Shut Down Viruses
Researchers have used RNAi gene therapy to turn off the viruses that cause hepatitis and HIV in mice. They are testing the technique in human trials against macular degeneration, an inherited condition, and a type of viral pneumonia.
Lab-grown Ligaments May Help Injured Sports Stars
US scientists bio-engineered anterior cruciate ligaments and used them to repair knee joints in rabbits. Eventually, the researchers hope to treat humans who suffer ruptured ligaments using the technique.
Cell Genesys, Medarex Show Combo Data
Cell Genesys, Inc. and Medarex, Inc. announced encouraging follow-up data from the ongoing Phase 1 clinical trial of Cell Genesys’ GVAX immunotherapy for prostate cancer, administered in combination with Medarex’s fully human anti-CTLA-4 antibody, ipilimumab (MDX-010).
FDA Clears First Suture That Uses DNA Technology
FDA has cleared for marketing the TephaFLEX Absorbable Suture, the first suture to be made from material created by a form of DNA technology. The product, used to hold soft tissue together for healing, is made of materials that break down in the body after a short time.
ABSTRACTS, REVIEWS AND SPECIAL REPORTS
Differentiation of Human Adult Skin-derived Neuronal Precursors into Mature Neurons
This article discusses the generation of autologous neurons from an accessible adult human source, adult human skin. This technique opens many potential therapeutic applications and has a great potential for the development of experimental studies on normal human neurons.
The Adult Human Heart as a Source for Stem Cells: Repair Strategies with Embryonic-like Progenitor Cells
In this article, the researchers discuss the potential for autologous repair or even cardiac regeneration with cells that follow a developmental pathway similar to embryonic cardiac precursors but without the inherent limitations associated with undifferentiated embryonic stem cells.