Cancer Stem Cell Development is Documented
U.S. scientists have clarified how normal stem cells become cancer stem cells, as well as how cancer stem cells can cause the formation of tumors.
Brain Tumor Researchers Find Their “Niche”
Brain tumors appear to arise from cancer stem cells (CSCs) that live within microscopic protective “niches” formed by blood vessels in the brain; and disrupting these niches is a promising strategy for eliminating the tumors and preventing them from re-growing, according to results of a study by investigators at St. Jude Children’s Research Hospital.
Researchers Make Diabetes and Stem Cell Breakthrough
A team of South Korean scientists has grown pancreatic beta cells, which can help treat diabetes, from stem cells taken from the umbilical cord blood of new born babies.
Turning a Cellular Sentinel into a Cancer Killer
Howard Hughes Medical Institute researchers have developed two strategies to reactivate the p53 gene in mice, causing blood, bone and liver tumors to self destruct.
Alzheimer’s Vaccine in a Patch
A patch which delivers a vaccine against Alzheimer’s disease through the skin has been shown to be safe and effective, a study has found.
GenVec Announces First Patient Treated with TNFerade(TM) for Head and Neck Cancer at University of Chicago
GenVec, Inc. has announced that the first patient has been dosed in a Phase I/II trial with TNFerade(TM) for head and neck cancer at the University of Chicago Medical Center. GenVec is sponsoring two separate Phase I/II studies at the University of Chicago to explore the use of TNFerade as a second-line treatment for unresectable, recurrent tumors, and as a first-line treatment for elderly or frail patients.
Cell Genesys Announces Encouraging Follow-Up Survival Data From Phase 2 Clinical Trial of GVAX(R) Immunotherapy for Pancreatic Cancer
Cell Genesys, Inc. has announced follow-up data from a Phase 2 clinical trial of GVAX(R) immunotherapy for pancreatic cancer in 60 patients with operable pancreatic cancer who received the immunotherapy after surgical resection of their tumor and adjuvant radiation and chemotherapy.
Introgen Reports that INGN 241 in Combination with Avastin(R) Results in Complete Tumor Regression
Introgen Therapeutics, Inc. has today the publication of data in Molecular Therapy, the journal of the American Society of Gene Therapy, highlighting the results of a preclinical study with INGN 241 in combination with Avastin(R) (Bevacizumab). Synergistic activity resulting in a curative therapeutic effect was seen in the treatment of lung cancer following the combination of the two agents.
Millipore’s HEScGRO(TM) Medium Advances Human Embryonic Stem Cell Research
Millipore Corporation today announced the availability of HEScGRO animal component-free medium for human embryonic stem cell research.
Cytori Receives U.S. 510(K) Regulatory Clearance for its Adipose Tissue Processing System with Related Celase(TM) Reagent
Cytori Therapeutics received U.S. 510(K) regulatory clearance from the Food and Drug Administration’s Center for Devices and Radiological Health (CDRH) for its adipose (fat) tissue processing system with related Celase(TM) tissue processing reagent.
Seoul Lab Clones Poodle
A source familiar with the cloning has reported that scientists at the College of Veterinary Medicine of Seoul National University (SNU) cloned a female Poodle midway through last year.
ABSTRACT, REVIEWS AND SPECIAL REPORTS
Maternal Microchimerism in Peripheral Blood in Type 1 Diabetes and Pancreatic Islet Cell Microchimerism
This paper describes experiments showing that cells passed from mother to child during pregnancy can differentiate into functioning islet beta cells that produce insulin in the child.