Volume 7.46 | Nov 27

Volume 7.46, November 27, 2006
     In this issue: Science | Policy | Business | NIH | CBER | Regulatory
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Top Stories

Researchers Identify Master Cardiac Stem Cell: Three US research groups claim that they can produce stem cells that give rise to different tissues found in the mammalian heart.
Article

Science

Another Boost For Stem Cell Research
University of New South Wales academics have proven that tumours can be prevented from forming when embryonic stem cells are transplanted.
Article

Cancer Stem Cells Source of Some Colon Tumors
Two recent studies involving laboratory mice indicate colon cancer stem cells may be the source of colon cancer tumors.
Article

Investigators Discover Modified Growth Control in Human Embryonic Stem Cells
Two papers published by University of Massachusetts Medical School Department of Cell Biology and Cancer Center investigators report striking changes in control of growth in human embryonic stem cells.
Article

Researchers Making Vaccine from Brain Tumour
A neurosurgeon from the University of California at San Francisco Medical Center has helped create made-to-measure vaccines using a person’s surgically removed tumour, and he’s started testing the concept in a small group of patients.
Article

Data From Investigator-Sponsored Trial of Oncophage(R) Cancer Vaccine in Glioma Presented at Immunotherapy Task Force Meeting at the Society of Neuro-Oncology’s Annual Meeting
Preliminary results from the first cohort of six patients in the study showed that Oncophage vaccination was associated with tumor-specific immune response in six treated patients with recurrent, high-grade glioma.
Article

Gene Therapy Shows Promise Against Hereditary Lung Disease
An experimental gene therapy to combat alpha-1 antitrypsin deficiency, a common hereditary disorder that causes lung and liver disease, has caused no harmful effects in patients and shows signs of being effective.
Article

Scientists Regenerate Wing In Chick Embryo
A research team at the Salk Institute for Biological Studies has been able to regenerate a wing in a chick embryo – a species not known to be able to regrow limbs – suggesting that the potential for such regeneration exists innately in all vertebrates, including humans.
Article

Journal Clarifies Stem Cell Report
The scientific journal Nature today issued a clarification of a recent report that human embryonic stem cells could be derived without harm to the embryo, but the journal affirmed the report’s scientific validity.
Article

Hwang Hopes to Resume Human Stem Cell Cloning
The government revoked his license for such work, but Hwang is preparing for the future by building a large research facility in Yongin, about 50 kilometers south of Seoul.
Article

ABSTRACTS, REVIEWS AND SPECIAL REPORTS

The Glimmering Promise of Gene Therapy
An examination of gene therapy: Past, present and future
Article

Policy

State and Philanthropies Clear Loans to California Stem Cell Institute
The California Institute for Regenerative Medicine received the final clearance from the state government for a $150 million loan so it can fund stem cell research.The institute also received a $31 million loan from nine philanthropic sources, giving it $181 million in loans to allow research grants, while the $3 billion publicly voted funds are tied up in court suits.
Article

Three Democratic Lawmakers Balk at Stem Cell Policies
In what one lawmaker says could signal gridlock on stem cell research in the upcoming legislative session, three Democrats have refused to sign a House committee report that they say doesn’t offer a “scientifically accurate” view.
Article

Iran in the Forefront When it Comes to Stem Cell Research
When it comes to stem cell research, Iran is cutting edge. Iran has some of the most liberal laws on stem cell research. Scientists say the clergy here define life as beginning three months after conception, which gives scientists access to human embryonic stem cells left over from fertilization trials.
Article

Business

ReNeuron and Millipore Announce Market Launch of ReNcell(TM) Neural Stem Cell Lines
These products are the only immortalised human somatic neural stem cell lines on the market today.
Article

CyGenics Signs Collaboration Agreement with the Blood Centre of Zhejiang Province
Leading heathcare company CyGenics Ltd has signed an agreement with the Blood Centre of Zhejiang Province (ZBC) in China for development work generating human T cells outside the body for the treatment of HIV, using CyGenics’ proprietary cellular growth technology.
Article

NeoStem, Inc. Appoints Innovative Leader In Competitive Business Procurement And Management To The Company’s Board Of Directors
NeoStem, Inc has announced that it has appointed Douglas W. Losordo, MD, a prominent authority in cardiology and emerging stem cell therapies, to the Company’s Scientific Advisory Board.
Article

NIH

Pancreatic Development and Regeneration: Toward Cellular Therapies for Diabetes (R01) (PA-07-056)
Link

Establishment of Multiple Principal Investigator Awards for the Support of Team Science Projects (NOT-OD-07-017)
Link

Non-Invasive Methods for Diagnosis and Progression of Diabetes, Kidney, Urological, Hematological and Digestive Diseases (R01) (PA-07-025)
Link

Developmental Biology and Regeneration of the Liver (R01) (PA-07-026)
Link

Right Heart Function in Health and Chronic Lung Diseases: (R01) (PA-07-043)
Link

Research Project Grant (Parent R01) (PA-07-070)
Link

CBER

CPG 7342.001: Chapter 42 – Blood and Blood Products – Inspection of Licensed and Unlicensed Blood Banks, Brokers, Reference Laboratories, and Contractors – Update of Military Contacts
Link

All new CBER information can be reached from the What’s New page at What’s New Page

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Regulatory

FOOD AND DRUG ADMINISTRATION (United States of America)

Electronic Submission of Regulatory Information, and Creating an Electronic Platform for Enhanced Information Management; Public Hearing
Link


ISCT

Call for Abstracts
On-line abstract submission for the 2007 ISCT Annual Meeting is now available through the ISCT Website. 
Submission deadline: February 16, 2007
Link

ISCT Membership
Renew your ISCT Membership for 2007 now!
Not a member?  Visit the ISCT website to learn about the benefits of membership.
Link

AABB-ISCT Cellular Therapy Audioconference Series
Link

Profiled Journal

Editor-in-Chief:
Robert Weinstein, MD
Chief, Division of Transfusion Medicine, UMass Memorial Medical Center, Worcester, MA.

The Journal of Clinical Apheresis provides the world’s premier source of current information in the field of apheresis. The Journal presents work in all aspects of basic and clinical research, practical applications, emerging technologies and regulation in apheresis and related fields including hematology, nephrology, neurology, rheumatology, transplantation, cellular therapies, blood banking, transfusion medicine, and others.

A subscription to the journal is a key benefit of ASFA membership, which ranges from $120-145 annually. To become a member please contact:

ASFA Head Office
375 West 5th Ave, Suite 201
Vancouver, BC V5Y IJ6, Canada
T 604-484-2851
F 604-874-4378
E [email protected]
www.apheresis.org

Please visit the website for all you need to know about publishing in or subscribing to the Journal of Clinical Apheresis:
http://www.interscience.wiley.com/journal/jca



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