Low Oxygen Preserves Usefulness of Stem Cells
Low levels of oxygen, or hypoxia, may help preserve the unique undifferentiated nature of stem or progenitor cells.
Placenta Expanded Cell Therapy Product Increases Umbilical Cord Blood Engraftment up to 500% in Bone Marrow Transplants
The Pre-Clinical results document that adding Pluristem’s PLX-I to UCB stem cells during the Bone Marrow Transplant (BMT) human cell engraftment in NOD SCID mice showed up to a 500% increased engraftment after irradiation and Chemotropic treatment.
New Stem Cell Research Targets Myocardial Ischemia
University of Iowa Hospitals and Clinics leaders announced that it is one of the first medical centers in the country participating in a novel clinical trial investigating if a patient’s own stem cells can treat a form of severe coronary artery disease.
Partial-match Cell Transplants For Children With Most Resistant Leukemia
St. Jude technique allows partial-match cell transplants for children with most resistant leukemia, boosting chance for cure while avoiding previous harsh forms of treatment
New University of Iowa Therapy May Help Prostate Cancer Patients
A team of University of Iowa Health Care researchers has launched an important clinical trial of a novel therapeutic that may eventually lead to new treatments for men diagnosed with prostate cancer.
Arteriocyte Inc. Completes Phase I Stem Cell Clinical Trial Enrollment
The study is evaluating the safety of ACY001, an adult stem cell therapy harvested from bone marrow to treat chronic ischemia, a serious form of heart disease.
Neurologix Announces Successful Completion of First Ever Phase I Gene Therapy Trial for Parkinson’s Disease
Neurologix, Inc. announced that it has successfully completed its landmark Phase I trial of gene therapy for Parkinson’s disease with statistically significant results.
Osiris Therapeutics Reports Positive Phase II Results Using PROCHYMAL(TM) in Treatment-Resistant Crohn’s Disease
This outpatient stem cell treatment resulted in a statistically significant reduction in disease severity of patients who had failed to respond to standard care.
Seven Plead Guilty in New York Body-parts Scandal
Seven New York funeral directors have quietly pleaded guilty since the summer to charges that they helped a biomedical company plunder cadavers for body parts that could be sold for huge profits.
ABSTRACTS, REVIEWS AND SPECIAL REPORTS
Human Neural Stem Cell Grafts Ameliorate Motor Neuron Disease in SOD-1 Transgenic Rats
The researchers found that Neural Stem Cell grafts can survive well in a neurodegenerative environment and exert powerful clinical effects and that at least a portion of these effects may be related to the ability of these grafts to express and release motor neuron growth factors delivered to host motor neurons via graft-host connections.
Production of Pancreatic Hormone–expressing Endocrine Cells from Human Embryonic Stem Cells
The searchers have developed a differentiation process that converts human embryonic stem (hES) cells to endocrine cells capable of synthesizing the pancreatic hormones insulin, glucagon, somatostatin, pancreatic polypeptide and ghrelin.