Researchers Enhance Safety And Effectiveness Of Therapeutic Virus That Fights Cancer
Mayo Clinic researchers working with colleagues in Germany have devised a much-needed multilevel safety feature for viruses used to treat cancer.
Gene Silencer Helps Shut Down Ovarian Cancer
Tiny fatty spheres (liposomes) loaded with genetic material called “short interfering RNA” (siRNA) were able to penetrate deeply into ovarian tumor cells and silence a targeted protein (FAK).
Mouse Mimics Chronic Leukemia, Will Aid Drug Development
A study by cancer researchers here reveals that a new strain of mice offers the first real animal model for an incurable form of chronic leukemia and should greatly aid the development of new drugs for the disease.
UC Davis Researchers Move Biotechnology Closer to Replacing Electronic Pacemakers
UC Davis researchers have successfully used a custom designed protein and gene delivery system to restore normal heart rhythms in pigs with electronic pacemakers, reducing their dependence on implanted devices.
Living Cell Technologies Lodges Application for Clinical Trial of its Type 1 Diabetes Treatment
Living Cell Technologies Ltd has announced that it has lodged an application with the New Zealand regulator MedSafe to conduct a Phase I/IIa clinical trial of its type 1 diabetes cell therapy product DiabeCell(R).
Doctors Test Ways to Grow Knee Cartilage
Doctors are testing new ways to spur cartilage to regrow in damaged knees, from implanted “cartilage plugs” to injections of bone-marrow stem cells.
Further Positive Phase II Results of Trinam Gene Therapy
Ark Therapeutics Group plc has announced further positive results from a Phase II trial of Trinam(R), its novel gene therapy to prevent blood vessels blocking in kidney dialysis patients who have undergone vascular access graft surgery.
Dendreon Submits Clinical and Non-Clinical Sections of Rolling BLA to FDA for PROVENGE to Treat Advanced Prostate Cancer Patients
Dendreon Corporation has announced that the Company has submitted the clinical and non-clinical sections of the rolling submission of a Biologics License Application (BLA) to the U.S. Food and Drug Administration (FDA) for PROVENGE® (sipuleucel-T) for the treatment of asymptomatic patients with metastatic, androgen-independent prostate cancer.
Human Tissue Products Recalled in U.S.
The tissue products, which were retrieved from corpses, were supplied by Donor Referral Services, a body parts broker in Raleigh, N.C., which launched the recall.
ABSTRACTS, REVIEWS & SPECIAL REPORTS
Human Embryonic Stem Cell Lines Derived from Single Blastomeres
In this study, the researchers report a series of ten separate experiments demonstrating that hES cells can be derived from single blastomeres.