Manchester Scientists Create New Bio-gel for 3D Cell Culture
The gel is the first pH neutral material made from combinations of dipeptides (pairs of amino acids) to provide an environment in which cells can be cultured under physiological conditions.
Double Transplants May Offer One Solution to Short Supply of Donated Kidneys
Transplanting a pair of kidneys with limited function into one patient can be just as successful as the standard procedure in which a patient receives a single kidney, according to new research at Wake Forest University Baptist Medical Center.
San Diego Facility Collects Embryos For Stem Cell Research
Scientists in San Diego are operating Stem Cell Resource, which is believed to be the first public embryo bank in the U.S.
Liquid Crystals Can Be Used To Report In Real Time On The Differentiation Of Embryonic Stem Cells
University of Wisconsin-Madison researchers at the NSF-funded Materials Research Science and Engineering Center (MRSEC) have shown that by straining mechanically the cells as they grow, it is possible to reduce significantly and almost eliminate the uncontrolled differentiation of stem cells.
MS Vaccine Testing to Start in US
A US company is set to begin a trial of a vaccine which it claims halts the progress of multiple sclerosis.
Cord Blood Growing Source for Transplants
“The stem cells from cord blood donations are easier to collect and less complicated than traditional bone marrow donations,” says Elizabeth Shpall, M.D., director of the new Cord Blood Bank at M. D. Anderson.
ReNeuron Completes Banking of Stem Cell Therapy
The ReNeuron Group has announced it has completed the scale-up and cell banking of its lead stem cell product for stroke, which gives the Company the potential to progress this therapy without the need to re-derive the cells from source material in the future.
Sanofi Gene Therapy Cuts Amputations
Injections of a Sanofi-Aventis experimental gene therapy treatment cut the risk of amputations in patients with severely decreased blood flow to the legs, according to results of a mid-stage trial reported
Hwang Set to Strike Back With New Stem Cell Tests
Disgraced cloning scientist Hwang Woo-suk and his team are seeking to prove that they did clone human embryonic stem cells.
Journal Publishes Proof First Cloned Dog Claim is True
His creator has been discredited and controversy has long surrounded him, but scientists have confirmed that an Afghan hound named Snuppy is the world’s first cloned dog.
Xencor Data Shows Engineering the “Fc” Region of Antibodies Makes Them More Toxic to Cancer Cells
Engineering the “Fc” region of monoclonal antibodies (mAbs) increases their toxicity to cancer cells, potentially improving the utility of targeted cancer therapies, according to research conducted at Xencor, which will be published in the March 14 print issue of the Proceedings of the National Academy of Sciences (PNAS).
ABSTRACTS, REVIEWS & SPECIAL REPORTS
The Effect of Three-Dimensional Co-Culture of Hepatocytes and Hepatic Stellate Cells on Key Hepatocyte Functions in vitro
This study shows that stellate cells facilitate spheroid formation, influence spheroid architecture, and are an effective method of preserving some aspects of hepatocyte function in the early stage of culture.
Ideal Rather than Actual Body Weight Should be Used to Calculate Cell Dose in Allogeneic Hematopoietic Stem Cell Transplantation
We have shown that CD34+ cell doses based upon IBW are better predictive of engraftment after autologous and allogeneic HSCT.