Tiny Self-assembling Cubes Could Carry Medicine, Cell Therapy
“Our group has developed a new process for fabricating three-dimensional micropatterned containers for cell encapsulation and drug delivery,” said David H. Gracias, who led the lab team.
Mice Created With Human Brain Cells
Scientists announced Monday that they had created mice with small amounts of human brain cells in an effort to make realistic models of neurological disorders such as Parkinson’s disease.
Researchers Report ‘Amazing Find’ with Stem Cells
The scientists have found a way to coax stem cells from adult mice to change into brain, nerve, heart and pancreatic cells.
OHSU Discovery Sheds Light into How Stem Cells Become Brain Cells
Continued research could result in new therapies for those who suffer brain injury, Parkinson’s disease and other conditions related to lost or damaged brain cells.
Engineered Stem Cells Show Promise for Sneaking Drugs into the Brain
Writing this week (Dec. 15, 2005) in the journal Gene Therapy, University of Wisconsin-Madison neuroscientist Clive Svendsen and his colleagues describe experiments that demonstrate that engineered human brain progenitor cells, transplanted into the brains of rats and monkeys, can effectively integrate into the brain and deliver medicine where it is needed.
USC Researchers Track Down the Stem Cells that Create Feathers
The stem cells that produce bird feathers have been visualized and analyzed for the first time, signifying the initial step in a scientific journey that may ultimately shed light on human organ regeneration.
Sweden to Establish Biobank of Babies’ Stem Cells
Sweden will set up a national biobank of stem cells collected from babies’ umbilical cords blood after they are born, the government said Thursday.
Gene Test Detects Heart Transplant Rejection
A simple blood test may detect whether a chronic heart transplant patient is rejecting their heart, and may reduce the need for invasive heart-muscle biopsies, according to the results of a multi-center study called CARGO (Cardiac Allograft Rejection Gene Expression Observational Study), led by NewYork-Presbyterian Hospital and Columbia University Medical Center and to be published in the December 19 The American Journal of Transplantation.
Gladstone Researchers Hone in on Differentiation of Heart Stem Cells
A team of scientists from the Gladstone Institute of Cardiovascular Disease (GICD) has identified a key factor in heart development that could help advance gene therapy for treating cardiac disorders.
Standing Up to Paraplegia with Gene Therapy
Elena Rugarli and colleagues from the National Neurological Institute in Milan have used gene therapy to save sensory and skeletal muscle nerve fibers from degeneration in mice with hereditary spastic paraplegia (HSP).
Gene-Therapy Tried for Parkinson’s
It’s a time of mixed excitement and caution: these first three studies are to see if gene therapy is safe to try, not to prove whether it works.
Doctors Take Sides on Face Transplant
Carnival atmosphere, reported suicide attempts by donor and recipient may complicate recovery.
$500,000 to Study Cancer Immunotherapy and Design Patient-Specific Cancer Vaccines
Dr. Carl June, professor of pathology and laboratory medicine at the School of Medicine and director of Translational Research at Penn’s Abramson Cancer Center, was awarded the Bristol-Myers Squibb Company Freedom to Discover Unrestricted Biomedical Research Grant. These five-year grants support pioneering, risk-taking, basic research scientists.
ABSTRACT, REVIEWS, & SPECIAL REPORTS
Human Embryonic Stem Cells
Eight prominent scientists in stem cell research argue that questions regarding the validity of recent South Korean stem cell experiments should be resolved not in the press but within the scientific community, and call for the authors of the disputed studies to cooperate with independent tests of the cell lines involved.
Impaired DNA Replication within Progenitor Cell Pools Promotes Leukemogenesis
The demonstration that replication-impaired, poorly competitive progenitor cell pools can promote tumorigenesis provides a new rationale for links between tumorigenesis and common human conditions of impaired DNA replication such as dietary folate deficiency, chemotherapeutics targeting dNTP synthesis, and polymorphisms in genes important for DNA metabolism.