Neural Stem Cells Are Long-lived
New studies in mice have shown that immature stem cells that proliferate to form brain tissues can function for at least a year — most of the life span of a mouse — and give rise to multiple types of neural cells, not just neurons.
Liver Failure Patients Get Own Stem Cells
Imperial College London physicians say they’ve successfully treated patients suffering liver failure by using the patients’ own bone marrow stem cells.
New Immune Cell Found to be a Key to Inflammatory Diseases
The molecular roots of inflammatory and autoimmune diseases such as asthma, arthritis, and multiple sclerosis (MS) have been discovered by a team of researchers led by The University of Texas M. D. Anderson Cancer Center.
Researchers Find Defects in Adult Stem Cell Niche May Cause Breast Cancer
Researchers at Georgetown’s Lombardi Comprehensive Cancer Center have found that the onset of breast cancer may be due to defects in somatic adult stem cell niches that exist long before tumors develop.
Increase in Stem Cell Subtype Indicates Better Survival Rate in Acute Lung Injury
According to the authors, the improved survival rate among 45 patients with ALI correlated with higher colony counts of a stem cell subtype called endothelial progenitor cells (EPCs).
Stem Cells as a Diagnotsic Tool for Atherosclerosis Risk
Undifferentiated cells circulating in the blood stream offer a tremendous potential for vascular tissue regeneration, as recent clinical trials proved.
Pioneering Gene Therapy Saves ‘Boy-in-a-bubble’
A former ‘boy in a bubble’ who once could have been killed by a common cold is now enjoying family life to the full, thanks to pioneering gene therapy.
Living Kidney ‘Paired Donation’ An Effective Strategy in Overcoming Donor-recipient Incompatibilities, Hopkins Study Shows
A Johns Hopkins study has affirmed the success of living kidney “paired donation” (KPD) as a means of efficiently finding more kidney donors who are a match for patients in need.
Red Blood Cells Fitted with Artificial Tails
They might look like sperm swimming backwards, but red blood cells have become the first living cells to be fitted with an artificial tail.
Hair-raising Stem Cells Identified: Swiss Study Shows That Hair Follicles Contain Bonafide Multipotent Stem Cells
Using an animal model, a research team led by Yann Barrandon at the EPFL (Ecole Polytechnique Federale de Lausanne) and the CHUV (Lausanne University Hospital) has discovered that certain cells inside the hair follicle are true multipotent stem cells, capable of developing into the many different cell types needed for hair growth and follicle replacement. In an article appearing in the Oct 3 advance online edition of the Proceedings of the National Academy of Sciences, they demonstrate that these holoclones can be used for long-term follicle renewal.
Wisconsin-based Group to Run Stem Cell Bank
A Wisconsin-based research group will run the nation’s first embryonic stem cell bank under a four-year, $16 million federal contract, officials announced Monday.
Researchers to Gain Wider Access to Knockout Mice
The National Institutes of Health (NIH) today announced contracts that will give researchers unprecedented access to two private collections of knockout mice, providing valuable models for the study of human disease and laying the groundwork for a public, genome-wide library of knockout mice.
American Society for Apheresis (ASFA) Call for Abstracts
The American Society for Apheresis (ASFA) invites apheresis professionals to submit abstracts for presentation at the ASFA 2006 Annual Meeting, to be held at the Venetian in Las Vegas from May 23-26, 2006.
ABSTRACT, REVIEWS, & SPECIAL REPORTS
ES Cell-derived Glial Precursors Contribute to Remyelination in Acutely Demyelinated Spinal Cord Lesions
These findings demonstrate that ESGPs transplanted into acutely demyelinated lesions can contribute to myelin repair.
Methods for Derivation of Human Embryonic Stem Cells
In this study, we introduce methods for the derivation of human embryonic stem cells (hESCs) depending on the quality of the blastocysts.
Motility and Growth of Human Bone-marrow Mesenchymal Stem Cells During Ex Vivo Expansion in Autologous Serum
Our results suggest that autologous human serum may provide sufficient ex vivo expansion of human bone-marrow mesenchymal stem cells possessing multidifferentiation potential and may be better than fetal bovine serum in preserving high motility.
Tumor Immunology, Immunomics and Targeted Immunotherapy for Central Nervous System Malignancies
The current state of immune-based treatment paradigms and future directions will be discussed, paying particular attention to targeted antibody strategies, adoptive cellular immunotherapy, and tumor vaccine approaches that have been studied in clinical trials for CNS neoplasms.