Complimentary Webinar: Feeder-independent growth of hESCs & hiPSCs using mTeSR(R)1
STEMCELL Technologies Applauds Feeder-free Derivation of Human Induced Pluripotent Stem Cells
Using adipose cells as the starting cell population and mTeSR(TM)1, a defined medium that allows the expansion of human embryonic and induced pluripotent stem cells without the use of feeders, the researchers were able to fully reprogram cells to the pluripotent state. [STEMCELL Technologies, Vancouver]
New Type of Adult Stem Cells Found in the Prostate
A new type of stem cell discovered in the prostate of adult mice can be a source of prostate cancer. [Columbia University Medical Center, New York]
How Stem Cells Make Skin
Scientists have discovered two proteins that control when and how a layer of cells at the base of the skin containing stem cells switch to being skin cells. [European Molecular Biology Laboratory, Monterotondo]
Mesoblast’s Proprietary Stem Cells Successfully Repair/Regenerate Damaged Intervertebral Disc Cartilage
Mesoblast Limited recently announced highly successful preclinical trial results of its adult stem cells in the treatment of degenerative intervertebral disc disease, the leading cause of low back pain. [Mesoblast Limited, Melbourne]
Osiris Therapeutics Announces Preliminary Results for Prochymal Phase III GvHD Trials
Recent preliminary results for two phase III trials showed Prochymal caused significant improvements in response rates in liver and gastrointestinal graft-versus-host disease, however neither trial reached its primary endpoint. [Osiris Therapeutics, Inc., Columbia]
ABSTRACTS, REVIEWS AND SPECIAL REPORTS
Interplay of Oct4 with Sox2 and Sox17: a Molecular Switch from Stem Cell Pluripotency to Specifying a Cardiac Fate
Here, the researchers identify the molecular mechanism underlying the dose-dependent dual action of Oct4 as both a gatekeeper for stem cell pluripotency and in driving cells toward specific lineages. [J Cell Biol]
Spontaneous Calcium Oscillations Regulate Human Cardiac Progenitor Cell Growth
The adult heart possesses a pool of progenitor cells stored in myocardial niches, but the mechanisms involved in the activation of this cell compartment are currently unknown. [Circ Res]
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Research and Development Scientist – Stem Cell Biology
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