Volume 10.20 | Jun 1

Cell Therapy News 10.20, June 1, 2009
     In this issue: Science | Policy | Business | NIH | CBER | Regulatory
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Top Stories

Adult Bone Marrow Stem Cells Injected into Skeletal Muscle Can Repair Heart Tissue: University at Buffalo researchers have demonstrated for the first time that injecting adult bone marrow stem cells into skeletal muscle can repair cardiac tissue, reversing heart failure.
Article

Science

Contact Lens Stem Cell Sight Aid
In a world-first breakthrough, University of New South Wales medical researchers have used stem cells cultured on a simple contact lens to restore sight to sufferers of blinding corneal disease.
Article

Activated Stem Cells in Damaged Lungs Could be First Step Toward Cancer
Stem cells that respond after a severe injury in the lungs of mice may be a source of rapidly dividing cells that lead to lung cancer, according to a team of American and British researchers.
Article

Healing With Light? Optical Technology Controls Living Cells
A new optical technology that lines up living cells and controls their movements has opened the door to better artificial tissues and wounds that heal faster with less scarring.
Article

Engineered Circuits Can Count Cellular Events
MIT and Boston University engineers have designed cells that can count and “remember” cellular events, using simple circuits in which a series of genes are activated in a specific order.
Article

Cytori Reports Publication of Cardiovascular Preclinical Study; Adipose Stem & Regenerative Cells Improve Function in Heart Attack Model
The APOLLO study is the first clinical trial to investigate uncultured adipose-derived stem and regenerative cells in heart attacks in human patients.
Article

International Stem Cell Corporation Reports Positive Pre-Clinical Trial Results From Human Corneal Epithelial Cells
International Stem Cell Corporation has received positive early results from animal trials designed to improve photorefractive keratectomy, a form of corrective laser eye surgery that offers an improved alternative to LASIK.
Article

University of Florida Makes Gene Therapy Breakthrough in Treating Severe Genetic Disorder
A dog born with a deadly disease that prevents the body from using stored sugar has survived 20 months and is still healthy after receiving gene therapy at the University of Florida.
Article

Fate Therapeutics Announces First Patient Treated in Phase 1b Clinical Trial of FT1050 for Hematopoietic Stem Cell Support
Fate Therapeutics, Inc. announced recently that the first patient has been treated in a Phase 1b clinical trial of FT1050, a small molecule Stem Cell Modulator designed to increase hematopoietic stem cell number and function through its activation of key pathways that guide cell fate.
Article

New Therapy Enlists Immune System to Boost Cure Rate in a Childhood Cancer
A multicenter research team has announced encouraging results for an experimental therapy using elements of the body’s immune system to improve cure rates for children with neuroblastoma, a challenging cancer of the nervous system.
Article

Cytori Completes Enrollment in First Adipose Stem & Regenerative Cell Therapy Trial for Chronic Heart Disease
The trial enrolled 27 patients was designed using the patients’ own cells were extracted from adipose tissue and processed for delivery at the point of care using Cytori’s Celution(R) System.
Article

ABSTRACTS, REVIEWS AND SPECIAL REPORTS

Emerging Potential of Transposons for Gene Therapy and Generation of Induced Pluripotent Stem Cells
The use of non-viral gene delivery approaches in conjunction with the latest generation transposon technology based on Sleeping Beauty or piggyBac transposons may potentially overcome stable gene transfer problems. (Blood)
Article

Free Bone Graft Attenuates Acute Rejection and in Combination with Cyclosporin A Leads to Indefinite Cardiac Allograft Survival1
The researchers report on a novel approach aimed at preventing acute vascular rejection, one of the major unresolved hurdles of clinical transplantation. (The Journal of Immunology)
Article

Generation of Induced Pluripotent Stem Cells from Human Blood
This paper describe the derivation of induced pluripotent stem cells from CD34+ mobilized human peripheral blood cells using retroviral transduction of OCT4/SOX2/KLF4/MYC. (Blood)
Article

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Policy

New Rules on Stem Cells Threaten Current Research
Many proponents of federal stem cell funding have concluded that the plan could have the opposite effect, putting off-limits for federal support much of the research underway, including work that the Bush administration endorsed.
Article

Maryland Stem Cell Research Commission Public Meeting Notice
Link

Business

Connexon Creative Launches Mammary Cell News
Mammary Cell News is a weekly e-newsletter that keeps members of the mammary cell community informed by providing the latest news from all areas of the field, including its science, research and business.

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Viewed Archived Issues

Commercial Partnership with STEMCELL Technologies Inc
ENKAM Pharmaceuticals A/S is pleased to announce that it has signed a licensing and development agreement with STEMCELL Technologies Inc, which is a leader in specialty cell culture media, cell separation products and ancillary reagents for life science research.
Article

Cellular Dynamics Licenses Key Patent Portfolio Surrounding Cardiovascular Progenitor Cells
Further broadening its leading IP position, Cellular Dynamics International recently announced that it has exclusively licensed a key patent portfolio for the differentiation of stem cells into human cardiovascular progenitor cells.
Article

£4m Grant for Stem Cell Research
A £4 million British Government grant has been awarded to scientists conducting research into stem cell treatments for broken bones.
Article

NIH

Ac”cell”erate your research with the NIH stimulus package and Robosep(R)
Link

Francis Collins Said to be Contender to Run NIH
Francis S. Collins, the scientist who led the U.S. government drive to map the human genetic code, is the leading candidate to run the National Institutes of Health, a source familiar with the selection process said.
Article

CBER

Licensed Biological Products with Supporting Documents
Link

Human Cell, Tissues and Cellular and Tissue-Based Products (HCT/P) List of Registered Establishments
Link

Regulatory

THERAPEUTICS GOODS ADMINISTRATION (Australia)

Online Survey: TGA Communications and Consultation Processes (New)
Link



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