Contact Lens Stem Cell Sight Aid
In a world-first breakthrough, University of New South Wales medical researchers have used stem cells cultured on a simple contact lens to restore sight to sufferers of blinding corneal disease.
Activated Stem Cells in Damaged Lungs Could be First Step Toward Cancer
Stem cells that respond after a severe injury in the lungs of mice may be a source of rapidly dividing cells that lead to lung cancer, according to a team of American and British researchers.
Healing With Light? Optical Technology Controls Living Cells
A new optical technology that lines up living cells and controls their movements has opened the door to better artificial tissues and wounds that heal faster with less scarring.
Engineered Circuits Can Count Cellular Events
MIT and Boston University engineers have designed cells that can count and “remember” cellular events, using simple circuits in which a series of genes are activated in a specific order.
Cytori Reports Publication of Cardiovascular Preclinical Study; Adipose Stem & Regenerative Cells Improve Function in Heart Attack Model
The APOLLO study is the first clinical trial to investigate uncultured adipose-derived stem and regenerative cells in heart attacks in human patients.
International Stem Cell Corporation Reports Positive Pre-Clinical Trial Results From Human Corneal Epithelial Cells
International Stem Cell Corporation has received positive early results from animal trials designed to improve photorefractive keratectomy, a form of corrective laser eye surgery that offers an improved alternative to LASIK.
University of Florida Makes Gene Therapy Breakthrough in Treating Severe Genetic Disorder
A dog born with a deadly disease that prevents the body from using stored sugar has survived 20 months and is still healthy after receiving gene therapy at the University of Florida.
Fate Therapeutics Announces First Patient Treated in Phase 1b Clinical Trial of FT1050 for Hematopoietic Stem Cell Support
Fate Therapeutics, Inc. announced recently that the first patient has been treated in a Phase 1b clinical trial of FT1050, a small molecule Stem Cell Modulator designed to increase hematopoietic stem cell number and function through its activation of key pathways that guide cell fate.
New Therapy Enlists Immune System to Boost Cure Rate in a Childhood Cancer
A multicenter research team has announced encouraging results for an experimental therapy using elements of the body’s immune system to improve cure rates for children with neuroblastoma, a challenging cancer of the nervous system.
Cytori Completes Enrollment in First Adipose Stem & Regenerative Cell Therapy Trial for Chronic Heart Disease
The trial enrolled 27 patients was designed using the patients’ own cells were extracted from adipose tissue and processed for delivery at the point of care using Cytori’s Celution(R) System.
ABSTRACTS, REVIEWS AND SPECIAL REPORTS
Emerging Potential of Transposons for Gene Therapy and Generation of Induced Pluripotent Stem Cells
The use of non-viral gene delivery approaches in conjunction with the latest generation transposon technology based on Sleeping Beauty or piggyBac transposons may potentially overcome stable gene transfer problems. (Blood)
Free Bone Graft Attenuates Acute Rejection and in Combination with Cyclosporin A Leads to Indefinite Cardiac Allograft Survival1
The researchers report on a novel approach aimed at preventing acute vascular rejection, one of the major unresolved hurdles of clinical transplantation. (The Journal of Immunology)
Generation of Induced Pluripotent Stem Cells from Human Blood
This paper describe the derivation of induced pluripotent stem cells from CD34+ mobilized human peripheral blood cells using retroviral transduction of OCT4/SOX2/KLF4/MYC. (Blood)
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