Breakthrough Method Produces Parkinson’s Disease Patient-specific Stem Cells Free of Harmful Reprogramming Genes
Whitehead Institute researchers have developed a novel method to remove potential cancer-causing genes during the reprogramming of skin cells from Parkinson’s disease patients into an embryonic-stem-cell-like state.
Technique May Help Stem Cells Generate Solid Organs
Stem cells can thrive in segments of well-vascularized tissue temporarily removed from laboratory animals which can then be seamlessly reconnected to the animal’s circulatory system
McMaster Study Sheds Light on How Stem Cells Develop into Blood Cells
Messages sent within stem cells through a specific pathway can trigger them to specialize and develop into blood cells, according to new research from the McMaster Stem Cell and Cancer Research Institute.
University of Colorado at Boulder Research Team Identifies Stem Cells that Repair Injured Muscles
A University of Colorado at Boulder research team has identified a type of skeletal muscle stem cell that contributes to the repair of damaged muscles in mice.
Massachusetts General Hospital to Use Genetics to Personalize Cancer Care
Cancer doctors at Massachusetts General Hospital plan within a year to read the genetic fingerprints of nearly all new patients’ tumors, a novel strategy designed to customize treatment.
Protein Complex Shown to Play Pivotal Role in Stem Cell Development in Two Stanford Studies
Scientists at the Stanford University School of Medicine have identified a protein complex important in controlling whether embryonic stem cells retain their ability to become any cell in the body.
BrainStorm’s Stem Cell Technology Demonstrates Efficacy in an Experimental Model of Parkinson’s Disease
Recent on-line publication by scientists demonstrate that human-derived adult Stem Cells may be induced to differentiate in vitro into neural-like cells and, once injected into the brain, improve impaired motor behavior in an experimental model of Parkinson’s disease.
Stem Cells Could Halt Osteoporosis, Promote Bone Growth
In a new study published researchers from the Research Institute of the McGill University Health Centre explain that tweaking mesenchymal stem cells with interferon gamma may promote bone growth.
Australian Scientists Develop Stem Cell Survival Technique
Researchers at the University of New South Wales have found a way to keep those cells alive so they can regenerate damaged tissue around them.
Pluristem Therapeutics Receives FDA Clearance to Begin First-In-Human?Placenta-Derived Stem Cell Clinical Trial
Pluristem Therapeutics Inc. announced recently that the US Food & Drug Administration has cleared the Company’s Investigational New Drug application to initiate a Phase I clinical trial for the treatment of Critical Limb Ischemia.
FDA Removes Clinical Hold From Aastrom Phase II IMPACT-DCM Clinical Trial
Aastrom Biosciences, Inc. recently reported that the U.S. Food and Drug Administration has removed the clinical hold from the Company’s U.S. Phase II IMPACT-DCM clinical trial and that patient enrollment would resume at the four initiated clinical sites.
Cardio3 BioSciences Treats Its First Patient with C-Cure, a Second-Generation Stem Cell Derived Therapy for Heart Failure
The patient, who was treated at the Cardiovascular Center of Aalst is participating in a Phase II/III clinical study to assess this second generation cell therapy in patients with heart failure.
TissueGene Announces Regulatory Allowance to Initiate Phase IIa Study of TG-C in South Korea for Osteoarthritis of the Knee
TissueGene, Inc. announced recently that its South Korean licensing partner Kolon Life Science, Inc. has received regulatory allowance from the Korea Food and Drug Administration (KFDA) to initiate a Phase IIa clinical trial of TissueGene-C in patients with severe osteoarthritis of the knee.
ABSTRACTS, REVIEWS AND SPECIAL REPORTS
Treatment of Type 1 Diabetes with Adipose Tissue-Derived Stem Cells Expressing Pancreatic Duodenal Homeobox 1
This paper reports the derivation of insulin-producing cells from human or rat ADSC by transduction with the pancreatic duodenal homeobox 1 (Pdx1) gene.
Loss of Proliferation and Differentiation Capacity of Aged Human Periodontal Ligament Stem Cells and Rejuvenation by Exposure to the Young Extrinsic Environment
In this study, the researchers compared the proliferation and differentiation capacity of periodontal ligament stem cells obtained from young and aged donors.
Allogeneic Hematopoietic Stem-Cell Transplantation for Leukocyte Adhesion Deficiency
Allogeneic hematopoietic stem-cell transplantation offers the possibility of curative therapy, and with patient numbers at any individual center being limited, this study surveyed the transplant experience at 14 centers worldwide.
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